Diltiazem

Generic name: Diltiazem (oral/injection)

Usage of Diltiazem

Diltiazem belongs to a class of medications called calcium-channel blockers. It works by relaxing the blood vessels so the heart does not have to pump as hard. Diltiazem also increases the supply of blood and oxygen to the heart.

Diltiazem oral is used in adults alone or in combination with other medicines to treat hypertension (high blood pressure) or symptoms of angina (chest pain). Lowering blood pressure may lower your risk of a stroke or heart attack.

Diltiazem injection is used in adults to treat certain heart rhythm disorders such as atrial fibrillation or atrial flutter, or dangerously rapid heartbeats (tachycardia).

Diltiazem side effects

Get emergency medical help if you have signs of an allergic reaction to diltiazem (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Diltiazem may cause serious side effects. Call your doctor at once if you have:

  • chest pain, fast, slow, or uneven heart rate;
  • a light-headed feeling, like you might pass out;
  • heart problems - swelling, rapid weight gain, feeling short of breath; or
  • liver problems - loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
  • Common diltiazem side effects may include:

  • swelling;
  • infections, flu symptoms;
  • trouble breathing;
  • headache, dizziness, weakness;
  • slower heart rate;
  • pain, bruising, swelling, or irritation where the medicine was injected;
  • nausea, upset stomach; or
  • rash.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Diltiazem

    You should not use diltiazem if you are allergic to it, or if you have:

  • a serious heart condition such as "sick sinus syndrome" or "AV block" (unless you have a pacemaker);
  • very low blood pressure;
  • if your heart cannot pump blood properly; or
  • if you have recently had a heart attack and you have a build-up of fluid in your lungs.
  • You may not be able to use diltiazem if you have:

  • heart failure;
  • certain heart rhythm disorders (such as 'Afib' or atrial flutter with Wolff-Parkinson-White syndrome);
  • a heart condition that causes you to have very fast heartbeats; or
  • if you are receiving an intravenous beta-blocker (such as atenolol, metoprolol, or propranolol).
  • To make sure this medicine is safe for you, tell your doctor if you have ever had:

  • congestive heart failure or heart problems;
  • low blood pressure or slow heart rate; or
  • liver disease.
  • It is not known whether diltiazem will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

    Tell your doctor if you are breastfeeding.

    How to use Diltiazem

    Use diltiazem exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.

    Diltiazem injection is given into a vein by a healthcare provider. Your heart rate will be constantly monitored using an electrocardiogram or ECG (sometimes called an EKG). Your blood pressure and other vital signs will also be watched closely.

    Diltiazem oral is taken by mouth. Your pharmacist can provide more information about how to take this medicine correctly.

    Your dose needs may change if you switch to a different brand, strength, or form of this medicine.

    Some forms of diltiazem oral cannot be crushed or chewed, and some forms can be opened and mixed with applesauce. Ask your pharmacist how to take this medicine.

    Your blood pressure and liver function will need to be checked often.

    If you have high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms.

    Store at room temperature away from moisture, heat, and light.

    Warnings

    You should not use diltiazem if you have very low blood pressure, a serious heart condition such as "sick sinus syndrome" or "AV block" (unless you have a pacemaker), or if you have recently had a heart attack and you have a build-up of fluid in your lungs.

    Before taking this medicine, tell your doctor if you have kidney disease, liver disease, or congestive heart failure.

    Diltiazem may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Do not stop taking this medication without first talking to your doctor. If you stop taking it suddenly, your condition may become worse.

    Diltiazem may be only part of a complete program of treatment that also includes diet, exercise, and other medications. Follow your diet, medication, and exercise routines very closely.

    If you are being treated for high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life. However, if you have symptoms of low blood pressure (dizziness, fainting, weakness, or blurred vision), call your doctor and stop taking diltiazem.

    What other drugs will affect Diltiazem

    Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.

    Many drugs can interact with diltiazem. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all other medicines you use.

    Disclaimer

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