Diovan HCT

Generic name: Hydrochlorothiazide And Valsartan
Drug class: Angiotensin II inhibitors with thiazides

Usage of Diovan HCT

Hydrochlorothiazide is a diuretic (water pill). Valsartan is an angiotensin II receptor blocker (sometimes called an ARB blocker).

Diovan HCT is a combination medicine used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.

Diovan HCT is given after other blood pressure medicines did not work or have stopped working.

Diovan HCT may also be used for purposes not listed in this medication guide.

Diovan HCT side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

In rare cases, Diovan HCT can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark colored urine.

Diovan HCT may cause serious side effects. Call your doctor at once if you have:

a light-headed feeling, like you might pass out;

eye pain, vision problems;

an unusual skin rash;

little or no urinating;

jaundice (yellowing of the skin or eyes);

easy bruising, unusual bleeding;

a seizure;

kidney problems--little or no urination, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath; or

signs of an electrolyte imbalance--dry mouth, increased thirst, confusion, feeling restless, vomiting, muscle pain or weakness, drowsiness, lack of energy, fast heartbeats, decreased urination.

Common side effects include:

cold symptoms such as stuffy nose, sneezing, sore throat;

dizziness; or

headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Diovan HCT

You should not use this medicine if you are allergic to valsartan or hydrochlorothiazide, or if you have:

decreased urination or are unable to urinate; or

an allergy to sulfa drugs.

If you have diabetes, do not use Diovan HCT together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking Diovan HCT with aliskiren if you have kidney disease.

Tell your doctor if you have ever had:

an electrolyte imbalance (such as low levels of potassium or magnesium, or high levels of calcium in your blood);

liver disease;

kidney disease;

gallstones;

lupus;

congestive heart failure;

gout, or high levels of uric acid in your blood;

asthma or allergies;

high cholesterol or triglyceride levels;

an allergy to penicillin;

glaucoma; or

if you are on a low-salt diet.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Valsartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

You should not breastfeed while using this medicine.

Diovan HCT is not approved for use by anyone younger than 18 years old.

Relate drugs

How to use Diovan HCT

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

You may take Diovan HCT with or without food.

Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medication, which can lead to severely low blood pressure or a serious electrolyte imbalance.

Your blood pressure will need to be checked often. Your blood and urine may also be tested if you have been vomiting or are dehydrated.

If you need surgery, tell the surgeon ahead of time that you are using Diovan HCT.

It may take up to 4 weeks for this medication to control your blood pressure. Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Store at room temperature away from moisture and heat.

Warnings

You should not use Diovan HCT if you are unable to urinate, or if you are allergic to sulfa drugs.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant.

If you have diabetes, do not use Diovan HCT together with any medication that contains aliskiren (a blood pressure medicine).

What other drugs will affect Diovan HCT

If you also take cholestyramine or colestipol, take your Diovan HCT dose 4 hours before or 4 hours after you take the other medicine.

Tell your doctor about all your current medicines. Many drugs can affect Diovan HCT, especially:

cyclosporine, digoxin, digitalis, lithium, or ritonavir;

all your heart or blood pressure medicines;

insulin or oral diabetes medicine;

a diuretic or "water pill";

opioid pain medicine;

a sleeping pill;

a muscle relaxer;

an antibiotic--rifabutin, rifampin, rifamycin, rifapentine;

cancer medicine--cyclophosphamide, methotrexate; or

NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

This list is not complete and many other drugs may affect Diovan HCT. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.