Diphenhydramine and magnesium salicylate

Generic name: Diphenhydramine And Magnesium Salicylate
Brand names: Doans PM
Dosage form: oral tablet (25 mg-580 mg)
Drug class: Analgesic combinations

Usage of Diphenhydramine and magnesium salicylate

Diphenhydramine is an antihistamine sometimes used as a sleep aid. Magnesium salicylate is a nonsteroidal anti-inflammatory drug (NSAID) in a group of drugs called salicylates (sa-LIS-il-ates).

Diphenhydramine and magnesium salicylate is a combination medicine that is used to treat back pain that keeps you awake during your normal sleeping hours.

Diphenhydramine and magnesium salicylate may also be used for purposes not listed in this medication guide.

Diphenhydramine and magnesium salicylate side effects

Get emergency medical help if you have signs of an allergic reaction: hives; wheezing, difficult breathing; feeling light-headed; swelling of your face, lips, tongue, or throat.

diphenhydramine and magnesium salicylate may cause serious side effects. Stop using diphenhydramine and magnesium salicylate and call your doctor at once if you have:

  • severe drowsiness;
  • painful or difficult urination;
  • ringing in your ears, hearing loss;
  • confusion; or
  • signs of stomach bleeding--feeling light-headed, ongoing stomach pain, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.
  • Common side effects of diphenhydramine and magnesium salicylate may include:

  • drowsiness;
  • dry eyes, blurred vision;
  • dry mouth, nose, or throat;
  • decreased urination;
  • heartburn, nausea, vomiting, gas;
  • constipation;
  • feeling restless or excited (especially in children); or
  • day-time drowsiness or "hangover" feeling after night-time use.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Diphenhydramine and magnesium salicylate

    You should not use diphenhydramine and magnesium salicylate if you are allergic to aspirin or other salicylates.

    Do not give this medicine to a child or teenager with a fever, flu symptoms, or chickenpox. Salicylates can cause Reye's syndrome, a serious and sometimes fatal condition in children. Ask a doctor before giving the medicine to a child younger than 12 years old.

    Magnesium salicylate may cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using magnesium salicylate, especially in older adults.

    Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

  • bleeding problems;
  • heartburn, stomach ulcer, or stomach bleeding;
  • an enlarged prostate or urination problems;
  • asthma or COPD, cough with mucus, or cough caused by smoking, emphysema, or chronic bronchitis;
  • heart disease, high blood pressure;
  • liver disease, cirrhosis, or if you drink more than 3 alcoholic beverages per day;
  • kidney disease;
  • arthritis, gout;
  • diabetes;
  • glaucoma; or
  • a thyroid disorder.
  • Ask a doctor before using this medicine if you are pregnant or breastfeeding.

    Taking this medicine during the last 20 weeks of pregnancy may cause serious kidney problems in the unborn baby, or bleeding in the mother or the baby during delivery.

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    How to use Diphenhydramine and magnesium salicylate

    Usual Adult Dose for Insomnia:

    Diphenhydramine-magnesium salicylate 25 mg-580 mg oral tablet:2 tablets orally at bedtime as needed with a full glass of water.

    Usual Adult Dose for Pain:

    Diphenhydramine-magnesium salicylate 25 mg-580 mg oral tablet:2 tablets orally at bedtime as needed with a full glass of water.

    Usual Pediatric Dose for Insomnia:

    Diphenhydramine-magnesium salicylate 25 mg-580 mg oral tablet:12 years or older: 2 tablets orally at bedtime as needed with a full glass of water.

    Usual Pediatric Dose for Pain:

    Diphenhydramine-magnesium salicylate 25 mg-580 mg oral tablet:12 years or older: 2 tablets orally at bedtime as needed with a full glass of water.

    Warnings

    Use this medicine exactly as directed. Taking too much diphenhydramine can lead to serious heart problems, seizures, coma, or death.

    Magnesium salicylate may cause stomach or intestinal bleeding, which can be fatal. Call your doctor at once if you have symptoms of stomach bleeding such as dizziness, black or bloody stools, or coughing up blood.

    Ask a doctor before giving the medicine to a child younger than 12 years old. Do not give this medicine to a child or teenager with a fever, flu symptoms, or chickenpox. Do not use this medicine to make a child sleepy.

    What other drugs will affect Diphenhydramine and magnesium salicylate

    Ask a doctor or pharmacist before using this medicine with any other drugs that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures).

    Ask a doctor or pharmacist if it is safe for you to use diphenhydramine and magnesium salicylate if you are also using:

  • a blood thinner--warfarin, Coumadin, Jantoven;
  • other NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others;
  • This list is not complete. Other drugs may affect diphenhydramine and magnesium salicylate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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