Diphtheria, tetanus, acellular pertussis, polio, hib vaccine

Generic name: Diphtheria, Tetanus, Acellular Pertussis, Polio, Hib Vaccine
Drug class: Vaccine combinations

Usage of Diphtheria, tetanus, acellular pertussis, polio, hib vaccine

Diphtheria, tetanus, and acellular pertussis vaccine (also known as DTaP) combined with inactivated poliovirus and Haemophilus B conjugate vaccine (also known as IPV and Hib) is a combination vaccine that is given to protect against infections caused by diphtheria, tetanus (lockjaw), pertussis (whooping cough), poliovirus, and Haemophilus influenzae type b. This vaccine works by causing the body to produce its own protection (antibodies) against these diseases. This vaccine is only given to babies and children who are 6 weeks to 4 years of age, and is given before the child's 5th birthday.

Diphtheria is a serious illness that can cause breathing difficulties, heart problems, nerve damage, pneumonia, and possibly death. The risk of serious complications is greater in very young children and the elderly.

Tetanus (also known as lockjaw) is a very serious illness that causes seizures and severe muscle spasms that can be strong enough to cause bone fractures of the spine. The disease continues to occur almost exclusively among people who do not get vaccinated or do not have enough protection from previous vaccines.

Pertussis (also known as whooping cough) is a serious disease that causes severe spells of coughing that can interfere with breathing. Pertussis can also cause pneumonia, long-lasting bronchitis, seizures, brain damage, and death.

Polio is a very serious infection that causes paralysis of the muscles, including the muscles that enable you to walk and breathe. A polio infection may leave a person unable to breathe without the help of a breathing machine. It may also leave a person unable to walk without leg braces or being confined to a wheelchair. There is no cure for polio.

Infection by Haemophilus influenzae type b (Hib) bacteria can cause life-threatening illnesses, such as meningitis, which affects the brain; epiglottitis, which affects the throat and can cause death by suffocation; pericarditis, which affects the heart; pneumonia, which affects the lungs; and septic arthritis, which affects the bones and joints.

Diphtheria, tetanus, and pertussis are serious diseases that can cause life-threatening illnesses. Although some serious side effects can occur after a dose of DTaP (usually from the pertussis vaccine part), this rarely happens. The chance of your child catching one of these diseases, and being permanently injured or dying as a result, is much greater than the chance of your child getting a serious side effect from the DTaP vaccine.

This vaccine is to be administered only by or under the supervision of your child's doctor or other authorized health care professional.

Diphtheria, tetanus, acellular pertussis, polio, hib vaccine side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  • Chest pain or tightness
  • confusion
  • coughing
  • crying, persistent and inconsolable, occurring within 48 hours and lasting 3 or more hours
  • decreased urination
  • diarrhea
  • dizziness
  • dry mouth
  • fainting
  • fever
  • increase in heart rate
  • lightheadedness
  • loss of appetite
  • nausea
  • noisy, rapid, or trouble breathing
  • sneezing
  • sore throat
  • stomach pain
  • sunken eyes
  • thirst
  • unusual tiredness or weakness
  • wrinkled skin
  • Incidence not known

  • Bluish color of the fingernails, lips, skin, palms, or nail beds
  • chills
  • cold or flu-like symptoms
  • drowsiness
  • fainting
  • fast heartbeat
  • general feeling of illness
  • hives
  • hoarseness
  • irritation
  • itching
  • joint pain, stiffness, or swelling
  • rash
  • redness of the skin
  • runny nose
  • severe headache
  • slow breathing
  • sneezing
  • stiff neck or back
  • stuffy nose
  • swelling of the eyelids, face, lips, hands, or feet
  • Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

    More common

  • Irritability
  • tenderness at the injection site
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
  • Incidence not known

  • Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • change in skin color at the injection site
  • paleness of the skin
  • sleepiness or unusual drowsiness
  • vomiting
  • Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

    Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

    Before taking Diphtheria, tetanus, acellular pertussis, polio, hib vaccine

    In deciding to use a vaccine, the risks of taking the vaccine must be weighed against the good it will do. This is a decision you and your doctor will make. For this vaccine, the following should be considered:

    Allergies

    Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

    Pediatric

    Appropriate studies have not been performed on the relationship of age to the effects of this vaccine in babies younger than 6 weeks of age and in children 5 years of age and older. Safety and efficacy have not been established.

    Make sure your doctor knows if your child was born prematurely. This vaccine may cause breathing problems (eg, apnea) to infants born prematurely.

    Geriatric

    No information is available on the relationship of age to the effects of this vaccine in geriatric patients.

    Breast Feeding

    Diphtheria Toxoid, AdsorbedPertussis VaccinePoliovirus Vaccine, InactivatedHaemophilus B Vaccine

    Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

    Tetanus Toxoid

    There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

    Interactions with Medicines

    Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this vaccine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

    Receiving this vaccine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Elivaldogene Autotemcel
  • Teplizumab-mzwv
  • Ublituximab-xiiy
  • Interactions with Food/Tobacco/Alcohol

    Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

    Other Medical Problems

    The presence of other medical problems may affect the use of this vaccine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Brachial neuritis (nerve problem) or
  • Guillain-Barré syndrome (nerve disorder with paralysis), history of after a vaccine with tetanus—Your doctor will decide if you or your child should receive this vaccine.
  • Brain or nerve disorder, unstable or progressive or
  • Encephalopathy (brain disease), history of within 7 days after a pertussis vaccine or
  • Epilepsy (seizures or convulsions), uncontrolled—Should not be used in patients with this condition.
  • Immunodeficiency disorder (weak immune system)—May not work as well in patients with this condition.
  • Relate drugs

    How to use Diphtheria, tetanus, acellular pertussis, polio, hib vaccine

    A nurse or other trained health professional will give your child this vaccine. It is given as a shot into one of your muscles.

    This vaccine is given as a 4-dose series at 2, 4, 6, and 15 to 18 months of age. Your child may receive a 5th dose of DTaP vaccine (eg, Daptacel® or Quadracel®) at 4 to 6 years of age.

    This vaccine may also be used to complete the first 4 doses in a 5-dose DTaP series in children who have received 1 or more doses of Daptacel® or 3-dose series of Vaxelis®.

    Your child may receive other vaccines at the same time as this one, but in a different body area. You should receive information sheets about all of the vaccines your child receives. Make sure you understand all of the information that is given to you.

    Your child may also receive a medicine to help prevent or treat some of the minor side effects of the vaccine, such as fever and soreness.

    It is important that you or your child receive all of the shots. Try to keep all scheduled appointments. Make another appointment as soon as possible if you or your child misses a dose of this vaccine.

    Warnings

    It is very important that you call the doctor right away if you or your child have any unwanted effects after receiving the vaccine. This may include fainting, seizures, a high fever, crying that will not stop, or severe redness or swelling where the shot was given.

    This vaccine may cause a serious type of allergic reaction called anaphylaxis, which can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have a rash, itching, swelling of the tongue and throat, or trouble breathing after you get the injection.

    Tell your child’s doctor about all other vaccines your child has had, especially if those vaccines were part of a series. This vaccine might be used to finish a series of vaccines.

    This vaccine will not treat an active infection. If your child has an infection due to diphtheria, tetanus, pertussis, polio, or Haemophilus influenzae type b, your child will need medicines to treat these infections. .

    Fainting may occur after you receive this vaccine. You may also have vision changes, numbness or tingling in your arms, hands, or feet, or jerky movements of the arms and legs. Call the doctor right away if you or your child have any of these symptoms.

    Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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