Dojolvi

Generic name: Triheptanoin
Drug class: Oral nutritional supplements

Usage of Dojolvi

Dojolvi is a synthetic is a medium chain triglyceride containing three odd-chain fatty acid molecules.

Dojolvi is a prescription medicine used to treat long-chain fatty acid oxidation disorders in adults and children.

Long-chain fatty acid oxidation disorders are rare genetic disorders that affect the body's ability to break down certain fats and convert them into energy. This can lead to low blood sugar, muscle weakness, heart problems, or life-threatening medical problems.

Dojolvi side effects

Get emergency medical help if you have signs of an allergic reaction to Dojolvi: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common Dojolvi side effects may include:

nausea, vomiting;

stomach pain; or

diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Dojolvi

To make sure Dojolvi is safe for you, tell your doctor if you have ever had: problems with your pancreas. Dojolvi may not work as well if your digestion is affected by a pancreas disorder.

Tell your doctor if you are pregnant or breastfeeding.

If you are pregnant, you may be enrolled in a pregnancy safety study to track the effects of triheptanoin on the baby.

Relate drugs

How to use Dojolvi

Usual Adult Dose of Dojolvi for Functional Gastric Disorder:

Recommended total daily dose (mL) = patients DCI (kcal) x target % dose of DCI / 8.3 kcal/mL -Round to nearest whole number -Divide total daily dose into at least 4 approximately equal individual doses Dose Initiation/Titration: Patients not currently taking a medium chain triglyceride (MCT) product: -Initiate at approximately 10% DCI divided into at least 4 individual doses. -Increase to recommended total daily dose over 2 to 3 weeks. Patients switching from another MCT product: -Discontinue previous MCT before therapy initiation. -Initiate at last tolerated MCT dose divided into at least 4 individual doses. -Increase total daily dosage by approximately 5% DCI every 2 to 3 days until target dosage is achieved. Comments: -Assess metabolic requirements by determining daily caloric intake (DCI) prior to dose calculations. -Recommended target is 35% of DCI. -Caloric value of this product is 8.3 kcal/mL.

Usual Pediatric Dose of Dojolvi for Functional Gastric Disorder:

Warnings

Before taking Dojolvi, tell your healthcare provider if you are taking a pancreatic lipase inhibitor, such as orlistat (Xenical), as it may affect how well Dojolvi works.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What other drugs will affect Dojolvi

Tell your doctor about all your other medicines, especially:

orlistat (alli, Xenical).

This list is not complete. Other drugs may interact with triheptanoin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.