Dornase alfa inhalation

Generic name: Dornase Alfa (inhalation)
Brand names: Pulmozyme
Dosage form: inhalation solution (2.5 mg/2.5 mL)
Drug class: Miscellaneous respiratory agents

Usage of Dornase alfa inhalation

Dornase alfa is used in people with cystic fibrosis to thin mucus in the airways. This may help improve lung function and lower the risk of infections.

Dornase alfa may also be used for purposes not listed in this medication guide.

Dornase alfa inhalation side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have worsened breathing problems.

Common side effects of dornase alfa may include:

sore throat;

chest pain, trouble breathing;

changes in the sound of your voice;

rash;

eye redness; or

fever.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Dornase alfa inhalation

You should not use dornase alfa if you are allergic to dornase alfa or other Chinese Hamster Ovary cell products.

Do not give this medicine to a child without medical advice.

Tell your doctor if you are pregnant or breastfeeding.

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How to use Dornase alfa inhalation

Usual Adult Dose for Cystic Fibrosis:

2.5 mg (1 single-use ampule) inhaled orally once daily using a recommended nebulizer/compressor systemComment:-Some patients may benefit from twice daily administration.Use:-Coadministration with standard therapies for the management of cystic fibrosis (CF) patients to improve pulmonary function-To reduce the risk of respiratory tract infections requiring parenteral antibiotics in CF patients with a Force Vital Capacity (FVC) of 40% or more

Usual Pediatric Dose for Cystic Fibrosis:

5 years or older:2.5 mg (1 single-use ampule) inhaled orally once daily using a recommended nebulizer/compressor systemComment:-Some patients may benefit from twice daily administration.Uses:-Coadministration with standard therapies for the management of cystic fibrosis (CF) patients to improve pulmonary function-To reduce the risk of respiratory tract infections requiring parenteral antibiotics in CF patients with a Force Vital Capacity (FVC) of 40% or more

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

What other drugs will affect Dornase alfa inhalation

Other drugs may affect dornase alfa, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Disclaimer

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