Duobrii

Generic name: Halobetasol And Tazarotene Topical
Brand names: Duobrii
Drug class: Topical antipsoriatics

Usage of Duobrii

Duobrii Lotion contains a combination of halobetasol and tazarotene. Halobetasol is a highly potent steroid. Tazarotene is a compound similar to vitamin A.

Duobrii Lotion is a prescription medicine used to treat plaque psoriasis (raised, silvery flaking and redness of the skin) in adults.

It is not known if Duobrii is safe and effective in children under 18 years of age.

Duobrii side effects

Get emergency medical help if you have signs of an allergic reaction to Duobrii Lotion: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • irritation of treated skin;
  • a sunburn;
  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;
  • high blood sugar - increased thirst, increased urination, dry mouth, fruity breath odor; or
  • possible signs of absorbing this medicine through your skin - weight gain (especially in your face or your upper back and torso), slow wound healing, thinning or discolored skin, increased body hair, muscle weakness, nausea, diarrhea, tiredness, mood changes, menstrual changes, sexual changes.
  • Common Duobrii side effects may include:

  • burning, stinging, redness, itching, pain, or swelling of treated skin;
  • redness or crusting around your hair follicles;
  • rash;
  • peeling skin; or
  • thinning skin.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Duobrii

    You should not use Duobrii if you are allergic to halobetasol or tazarotene, or if you are pregnant.

    To make sure Duobrii is safe for you, tell your doctor if you have ever had:

  • eczema;
  • any type of skin infection;
  • liver disease; or
  • an adrenal gland disorder.
  • Steroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes.

    Do not use Duobrii Lotion if you are pregnant. It could harm the unborn baby or cause birth defects. Use effective birth control to prevent pregnancy while you are using this medicine.

    You may need to have a negative pregnancy test before starting this treatment. You should start using Duobrii Lotion during a normal menstrual period, to be sure you are not pregnant.

    Stop using this medicine and tell your doctor right away if you become pregnant, if you stop using birth control, or if you miss a menstrual period.

    It may not be safe to breastfeed while using halobetasol and tazarotene. Ask your doctor about any risk. If you apply this medicine to your chest, avoid areas that may come into contact with the baby's mouth.

    This medicine is not approved for use by anyone younger than 18 years old.

    Relate drugs

    How to use Duobrii

    Usual Adult Dose for Plaque Psoriasis:

    Apply a thin layer of lotion to the affected area(s) once daily; discontinue therapy when control is achieved Use: For the topical treatment of plaque psoriasis

    Warnings

    Duobrii Lotion can cause birth defects. Do not use if you are pregnant. Use effective birth control to prevent pregnancy.

    Stop using this medicine and tell your doctor right away if you become pregnant, if you stop using birth control, or if you miss a menstrual period.

    What other drugs will affect Duobrii

    Tell your doctor about all your other medicines, especially:

  • an antibiotic or other medicine that can make your skin more sensitive to sunlight; or
  • any other steroid medicine used on the skin, taken by mouth, or injected.
  • This list is not complete. Other drugs may interact with halobetasol and tazarotene topical, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

    Disclaimer

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