Duramorph PF injection

Generic name: Morphine (injection)
Drug class: Opioids (narcotic analgesics)

Usage of Duramorph PF injection

Duramorph PF is an opioid medicine used to treat severe chronic pain in adults and children.

Duramorph PF may also be used for purposes not listed in this medication guide.

Duramorph PF injection side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Opioid medicine can slow or stop your breathing, and death may occur. A person caring for you should give naloxone and/or seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

Duramorph PF may cause serious side effects. Call your doctor at once if you have:

slow heart rate, sighing, shallow breathing, breathing that stops;

extreme drowsiness, feeling like you might pass out;

flushing (sudden warmth, redness, or tingly feeling);

a seizure;

high levels of serotonin in the body--agitation, hallucinations, fever, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, diarrhea; or

low cortisol levels-- nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.

Serious breathing problems may be more likely in older adults and people who are debilitated or have wasting syndrome or chronic breathing disorders.

Common side effects of Duramorph PF may include:

breathing problems;

drowsiness, dizziness;

constipation, nausea, vomiting;

sweating; or

numbness, tingling, or cold feeling in your hands and feet.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Duramorph PF injection

You should not use this medicine if you have ever had an allergic reaction to Duramorph PF or other opioid medicines, or if you have:

severe asthma or breathing problems;

a stomach or bowel obstruction (including paralytic ileus); or

if you have taken an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine.

Tell your doctor if you have ever had:

breathing problems, sleep apnea (breathing that stops during sleep);

a head injury, brain tumor, or seizures;

a drug or alcohol addiction, or mental illness;

urination problems;

liver or kidney disease; or

pancreatitis.

If you use opioid medicine during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using opioid medicine if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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How to use Duramorph PF injection

Follow the directions on your prescription label and read all medication guides or instruction sheets. Never use Duramorph PF in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to use more of Duramorph PF.

Never share opioid medicine with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.

Duramorph PF is injected into a muscle or a vein. This medicine injection is sometimes given with an infusion pump that controls your dosing.

You may have withdrawal symptoms if you stop using Duramorph PF suddenly. Ask your doctor before stopping the medicine.

Store at room temperature away from moisture and heat. Keep the auto-injector in its original container until you are ready to use it.

Keep your medicine in a place where no one can use it improperly.

Do not keep leftover medicine. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist about a drug take-back program, or flush the unused medicine down the toilet.

Warnings

MISUSE OF OPIOID MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep Duramorph PF where others cannot get to it.

Using opioid medicine during pregnancy may cause life-threatening withdrawal symptoms in the newborn.

Fatal side effects may occur if you also drink alcohol or use other drugs that cause drowsiness or slow breathing.

What other drugs will affect Duramorph PF injection

Many other drugs can be dangerous when used with opioid medicine. Tell your doctor if you also use:

other opioid medicines;

a benzodiazepine sedative like Valium, Klonopin, or Xanax;

sleep medicine, muscle relaxers, or other drugs that make you drowsy; or

drugs that affect serotonin, such as antidepressants, stimulants, or medicine for migraines or Parkinson's disease.

This list is not complete. Many drugs may affect Duramorph PF, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.