Ecallantide

Generic name: Ecallantide
Brand names: Kalbitor
Dosage form: subcutaneous solution (10 mg/mL)
Drug class: Hereditary angioedema agents

Usage of Ecallantide

Ecallantide is used to treat attacks of hereditary angioedema (an immune system disorder). ecallantide is for use in adults and children at least 12 years old.

Ecallantide is not a cure for hereditary angioedema.

Ecallantide may also be used for purposes not listed in this medication guide.

Ecallantide side effects

Ecallantide can cause a serious allergic Reaction within 1 hour after injection. Tell your caregivers right away if you have:

  • chest pain or tightness, fast or weak heartbeat;
  • wheezing, cough, throat irritation, trouble breathing;
  • hoarse voice, tight feeling in your throat, trouble swallowing;
  • swelling of your lips, tongue, or throat;
  • swelling or redness in your face;
  • itching, rash, or hives;
  • flushing (warmth, redness, or tingly feeling);
  • sneezing, runny or stuffy nose; or
  • dizziness, feeling like you might pass out.

    • An allergic reaction may have the SAMe symptoms as hereditary angioedema. Your caregivers will watch you closely and will quickly treat an allergic reaction.

    Common side effects of ecallantide may include:

  • headache;
  • nausea, diarrhea;
  • fever;
  • stuffy nose, sore throat; or
  • skin reactions where the medicine was injected (redness, rash, itching, bruising, swelling).

    • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Ecallantide

    If possible during an emergency, tell your caregivers you have any type of allergy. Make sure any follow-up doctor knows you received ecallantide.

    You should not be treated with ecallantide if you are allergic to it.

    If possible during an emergency, tell your caregivers if you are pregnant or breastfeeding.

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    How to use Ecallantide

    Usual Adult Dose for Hereditary Angioedema:

    30 mg suBCUTAneously in three 10 mg injections; may repeat an additional 30 mg within 24 hours if attack persists.

    Usual Pediatric Dose for Hereditary Angioedema:

    12 years and older: 30 mg subcutaneously in three 10 mg injections; may repeat an additional 30 mg within 24 hours if attack persists.

    Warnings

    Ecallantide can cause a serious allergic reaction within 1 hour after injection. Symptoms include wheezing, cough, trouble breathing or swallowing, itching, hives, dizziness, fainting, or swelling in your face or throat.

    What other drugs will affect Ecallantide

    Other drugs may affect ecallantide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

    Disclaimer

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