Edaravone oral/injection
Generic name: Edaravone (oral/injection)
Drug class:
Miscellaneous central nervous system agents
Usage of Edaravone oral/injection
Edaravone is used to treat adults with amyotrophic lateral sclerosis (ALS).
Edaravone may also be used for purposes not listed in this medication guide.
Edaravone oral/injection side effects
Edaravone can cause serious allergic Reactions. Some side effects may occur during or after the injection. Tell your medical caregiver if you feel dizzy, nauseated, light-headed, itchy, sweaty, or have a headache, chest tightness, back pain, trouble breathing, or swelling in your face.
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Edaravone may cause serious side effects. Call your doctor at once if you have:
Common side effects of edaravone may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Edaravone oral/injection
You should not be treated with edaravone if you are allergic to it.
Tell your doctor if you have ever had:
It is not known if edaravone will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Ask a doctor if it is safe to breastfeed while using edaravone.
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How to use Edaravone oral/injection
Usual Adult Dose for Amyotrophic Lateral Sclerosis:
Initial treatment cycle:-Intravenous infusion: 60 mg once daily over 60 minutes for 14 days, followed by a 14-day drug-free period. -Oral suspension: 105 mg (5 mL) once daily orally or via feeding tube in the morning after overnight Fasting for 14 days, followed by a 14-day drug-free period. Subsequent treatment cycles:-Intravenous infusion: 60 mg once daily over 60 minutes for 10 days out of 14-day periods, followed by 14-day drug-free periods. -Oral suspension: 105 mg (5 mL) once daily orally or via feeding tube in the morning after overnight fasting for 10 days out of 14-day periods, followed by 14-day drug-free periods. Oral administration relative to type of food consumption:-High-fat meal (800 -1000 calories, 50% fat): 8 hours before administration and one hour after administration.-Low-fat meal (400-500 calories, 25% fat): 4 hours before administration and one hour after administration.-Caloric supplement (250 calories, e.g., protein drink): 2 hours before administration and one hour after administration.Comments:-Administer each 60 mg dose as 2 consecutive 30 mg IV infusion bags over a total of 60 minutes (infusion rate approximately 1 mg per minute [3.33 mL per minute]).-Discontinue infusion at first sign of hypersensitivity reaction. Use: For the treatment of Amyotrophic lateral sclerosis (ALS)
Warnings
Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.
What other drugs will affect Edaravone oral/injection
Other drugs may affect edaravone, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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