Empliciti
Generic name: Elotuzumab
Drug class:
Miscellaneous antineoplastics
Usage of Empliciti
Empliciti is a monoclonal antibody that blocks a certain protein in the body that can affect tumor cell growth. Monoclonal antibodies are made to target and destroy only certain cells in the body. This may help to protect healthy cells from damage.
Empliciti is used in combination chemotherapy to treat multiple myeloma (bone marrow cancer).
Empliciti is given together with either lenalidomide or pomalidomide, and a steroid medicine called Dexamethasone.
Lenalidomide (Revlimid) is available only under a special program. You must be registered in the program and understand the risks and benefits of taking this medicine.
Empliciti side effects
Get emergency medical help if you have signs of an allergic reaction to Empliciti: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your caregiver right away if you feel dizzy, itchy, chilled, feverish, light-headed, or short of breath.
Call your doctor at once if you have:
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common Empliciti side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Empliciti
You should not be treated with Empliciti if you are allergic to elotuzumab.
Tell your doctor if you have any type of infection.
Using Empliciti may increase your risk of developing other types of cancer. Ask your doctor about your specific risk.
Empliciti is used together with lenalidomide or pomalidomide, which must not be taken during pregnancy. Lenalidomide and pomalidomide are known to cause life-threatening birth defects or death of a baby if the mother or the father is taking the medicine at the time of conception or during pregnancy. Even one dose of lenalidomide or pomalidomide can cause major birth defects.
Stop using these medicines and call your doctor at once if you quit using birth control, if your period is late, or if you think you might be pregnant.
Lenalidomide and pomalidomide are available only from a certified pharmacy under a special program. You must be registered in the program and agree to use birth control measures as required.
You should not breast-feed while using Empliciti with lenalidomide and dexamethasone.
Relate drugs
- Abiraterone
- Abiraterone, micronized
- Adagrasib
- Adstiladrin
- Altretamine
- Amivantamab
- Amivantamab-vmjw
- Arsenic trioxide
- Asparaginase Erwinia chrysanthemi
- Asparaginase erwinia chrysanthemi recombinant-rywn
- Asparlas
- Axicabtagene ciloleucel
- Azacitidine
- Azacitidine (Injection)
- Azacitidine (Oral)
- Abecma
- Bacillus of calmette and guerin vaccine, live (Intradermal)
- Bacillus of calmette and guerin vaccine, live (Intravesical)
- BCG intravesical
- Belantamab mafodotin
- Belantamab mafodotin-blmf
- Belzutifan
- Besponsa
- Bexarotene
- Bexarotene (Oral)
- Blenrep
- Brexucabtagene autoleucel
- Breyanzi
- Calaspargase pegol
- Calaspargase pegol-mknl
- Camptosar
- Carvykti
- Ciltacabtagene autoleucel
- Danyelza
- Dinutuximab
- Elahere
- Elotuzumab
- Elzonris
- Empliciti
- Enasidenib
- Enfortumab vedotin
- Enfortumab vedotin-ejfv
- Erwinaze
- Hexalen
- Hycamtin (Topotecan Intravenous)
- Hycamtin (Topotecan Oral)
- Hycamtin oral/injection
- Idecabtagene vicleucel
- Idhifa
- Imlygic
- Inotuzumab ozogamicin
- Irinotecan
- Irinotecan liposomal
- Irinotecan liposome
- Ivosidenib
- Kimmtrak
- Krazati
- Kymriah
- Lartruvo
- Levamisole
- Lisocabtagene maraleucel
- Loncastuximab tesirine
- Loncastuximab tesirine-lpyl
- Lumakras
- Lumoxiti
- Lunsumio
- Lysodren
- Matulane
- Mirvetuximab soravtansine
- Mirvetuximab soravtansine-gynx
- Mitotane
- Mogamulizumab
- Mogamulizumab-kpkc
- Mosunetuzumab
- Mosunetuzumab-axgb
- Moxetumomab pasudotox
- Moxetumomab pasudotox-tdfk
- Nadofaragene firadenovec-vncg
- Naxitamab
- Naxitamab-gqgk
- Novaplus Irinotecan Hydrochloride
- Olaratumab
- Olutasidenib
- Omacetaxine
- Oncaspar
- Onivyde
- Onureg
- Padcev
- Pegaspargase
- Polatuzumab vedotin
- Polatuzumab vedotin-piiq
- Polivy
- Poteligeo
- Procarbazine
- Rezlidhia
- Rozanolixizumab-noli
- Rybrevant
- Rylaze
- Rystiggo
- Sacituzumab govitecan
- Sacituzumab govitecan-hziy
- Selinexor
- Sotorasib
- Synribo
- Tagraxofusp
- Tagraxofusp-erzs
- Talimogene laherparepvec
- Talquetamab
- Talquetamab-tgvs
- Talvey
- Targretin
- Targretin (Bexarotene Oral)
- Tazemetostat
- Tazverik
- Tebentafusp
- Tebentafusp-tebn
- Tecartus
- Teclistamab
- Teclistamab-cqyv
- Tecvayli
- Theracys
- Tibsovo
- Tice BCG
- Tice BCG Live (for intravesical use)
- Tisagenlecleucel
- Tisotumab vedotin
- Tisotumab vedotin-tftv
- Tivdak
- Topotecan (Intravenous)
- Topotecan (Oral)
- Topotecan oral/injection
- Tretinoin
- Tretinoin (Oral)
- Trisenox
- Trodelvy
- Unituxin
- Venclexta
- Venetoclax
- Verteporfin
- Vesanoid
- Vidaza
- Visudyne
- Welireg
- Xpovio
- Xpovio 40 mg once-weekly
- Xpovio 40 mg twice-weekly
- Xpovio 60 mg twice-weekly
- Xpovio 80 mg twice-weekly
- Yescarta
- Yonsa
- Yonsa (Abiraterone Oral)
- Yonsa (Abiraterone, micronized Oral)
- Zynlonta
- Zytiga
How to use Empliciti
Usual Adult Dose for Multiple Myeloma:
10 mg/kg IV every week for the first 2 cycles and every 2 weeks thereafter until disease progression or unacceptable toxicity: -Cycles 1 and 2: 10 mg/kg IV once a week on days 1, 8, 15, and 22 of a 28-day cycle -Cycle 3 and beyond: 10 mg/kg IV once every 2 weeks on days 1 and 15 of a 28-day cycle Manufacturer recommended infusion rate (at the recommended concentration of 25 mg/mL): CYCLE 1, DOSE 1: -Time interval 0 to 30 min; Rate 0.5 mL/min -Time interval 30 to 60 min; Rate 1 mL/min -Time interval 60 min or more; Rate 2 mL/min CYCLE 1, DOSE 2: -Time interval 0 to 30 min; Rate 3 mL/min -Time interval 30 min or more; Rate 4 mL/min CYCLE 1, DOSE 3 AND 4 AND ALL SUBSEQUENT CYCLES: -Rate 5 mL/min Comments: -The length of a cycle is 28 days. -This drug is given in combination with lenalidomide and dexamethasone; refer to the dexamethasone and lenalidomide prescribing information for additional information. -Patients should be premedicated 45 to 90 minutes before administration of elotuzumab with dexamethasone, an antipyretic, an H1 blocker, and an H2 blocker. The manufacturer recommends: Dexamethasone 28 mg orally 3 to 24 hours before the elotuzumab infusion plus dexamethasone 8 mg IV 45 to 90 minutes prior to infusion; on days that elotuzumab is not administered but dexamethasone is due (e.g., days 8 and 22 of cycle 3 and beyond), administer the standard dexamethasone dose (40 mg orally) AND acetaminophen 650 to 1000 mg orally AND diphenhydramine 25 to 50 mg orally or IV (or equivalent H1 blocker) AND ranitidine 50 mg IV or 150 mg orally (or equivalent H2 blocker). Use: In combination with lenalidomide and dexamethasone for the treatment of patients with multiple myeloma who have received 1 to 3 prior therapies
Warnings
Do not use Empliciti with lenalidomide or pomalidomide if you are pregnant, or if you are a man and your sexual partner is pregnant. You will be required to use birth control to prevent pregnancy before, during, and shortly after treatment with these medicines.
What other drugs will affect Empliciti
Other drugs may interact with elotuzumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Popular Keywords
- metformin obat apa
- alahan panjang
- glimepiride obat apa
- takikardia adalah
- erau ernie
- pradiabetes
- besar88
- atrofi adalah
- kutu anjing
- trakeostomi
- mayzent pi
- enbrel auto injector not working
- enbrel interactions
- lenvima life expectancy
- leqvio pi
- what is lenvima
- lenvima pi
- empagliflozin-linagliptin
- encourage foundation for enbrel
- qulipta drug interactions