Emtricitabine, lopinavir, ritonavir, and tenofovir

Generic name: Emtricitabine, Lopinavir, Ritonavir, And Tenofovir
Brand names: AccessPak For HIV PEP Expanded With Kaletra
Dosage form: oral kit (-)
Drug class: Antiviral combinations

Usage of Emtricitabine, lopinavir, ritonavir, and tenofovir

Emtricitabine, lopinavir, ritonavir, and Tenofovir are antiviral medicines that prevent human immunodeficiency virus (HIV) from multiplying in your body.

Emtricitabine, lopinavir, ritonavir, and tenofovir is a combination medicine used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). emtricitabine, lopinavir, ritonavir, and tenofovir is not a cure for HIV or AIDS.

Emtricitabine, lopinavir, ritonavir, and tenofovir may also be used for purposes not listed in this medication guide.

Emtricitabine, lopinavir, ritonavir, and tenofovir side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Early symptoms of lactic acidosis may get worse over time and this condition can be fatal. Get emergency medical help if you have even mild symptoms: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, fast or uneven heart rate, dizziness, or feeling very weak or tired.

Emtricitabine, lopinavir, ritonavir, and tenofovir may cause serious side effects. Call your doctor at once if you have:

  • severe dizziness, fainting, fast or pounding heartbeats;
  • vision changes;
  • increased urination or extreme thirst;
  • severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
  • penis erection that is painful or lasts longer than 4 hours;
  • signs of new infection--fever, chills, skin lesions, or cough with yellow or green mucus;
  • liver problems--nausea, upper stomach pain, itching, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • kidney problems--little or no urination, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath; or
  • severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
  • Common side effects of emtricitabine, lopinavir, ritonavir, and tenofovir may include:

  • diarrhea, nausea, vomiting, stomach pain;
  • headache, dizziness, feeling tired;
  • depressed mood, sleep problems (insomnia), strange dreams;
  • mild skin rash; or
  • changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Emtricitabine, lopinavir, ritonavir, and tenofovir

    You should not take this medicine if you have severe liver or kidney disease, or if you are allergic to emtricitabine (Emtriva, Atripla), lopinavir (Kaletra), ritonavir (Norvir), or tenofovir (Viread). Do not take this medicine with other medicines that also contain emtricitabine or tenofovir (Atripla, Emtriva, Viread).

    Some medicines can interact with emtricitabine, lopinavir, ritonavir, and tenofovir and should not be used at the same time. Your doctor may need to change your treatment plan if you use any of the following drugs:

  • alfuzosin;
  • lovastatin or simvastatin;
  • St. John's wort;
  • pimozide;
  • midazolam or triazolam;
  • rifampin;
  • sildenafil, Viagra (or Revatio for pulmonary arterial hypertension); or
  • an ergot medicine such as D.H.E. 45, Ergomar, Cafergot, Ergotrate, Methergine, Migergot, or Migranal.
  • To make sure emtricitabine, lopinavir, ritonavir, and tenofovir is safe for you, tell your doctor if you have:

  • liver or kidney disease;
  • heart disease or heart rhythm disorder;
  • low levels of potassium in your blood;
  • a bleeding disorder such as hemophilia;
  • osteopenia (low bone mineral density); or
  • pancreas problems, diabetes, or high cholesterol.
  • Some people taking this medicine develop a serious condition called lactic acidosis. This may be more likely in women, in people who are overweight or have liver disease, and in people who have taken HIV/AIDS medication for a long time. Talk with your doctor about your risk.

    It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.

    Women with HIV or AIDS should not breast-feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

    Do not give this medicine to a child without medical advice.

    Relate drugs

    Warnings

    You should not take emtricitabine, lopinavir, ritonavir, and tenofovir if you have severe liver or kidney disease, or if you are allergic to emtricitabine (Emtriva, Atripla), lopinavir (Kaletra), ritonavir (Norvir), or tenofovir (Viread). Do not take this medicine with other medicines that also contain emtricitabine or tenofovir (Atripla, Emtriva, Viread).

    Some medicines can cause unwanted or dangerous effects when used with emtricitabine, lopinavir, ritonavir, and tenofovir. Your doctor may need to change your treatment plan if you use certain medicines.

    Get emergency medical help if you have even mild symptoms such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, fast or uneven heart rate, dizziness, or feeling very weak or tired.

    What other drugs will affect Emtricitabine, lopinavir, ritonavir, and tenofovir

    This medicine can harm your kidneys. This effect is increased when you also use certain other medicines, including: antivirals, chemotherapy, injected antibiotics, medicine for bowel disorders, medicine to prevent organ transplant rejection, and some pain or arthritis medicines (including aspirin, Tylenol, Advil, and Aleve). You may need dose adjustments or special tests when taking any of these other medications.

    Many drugs can interact with emtricitabine, lopinavir, ritonavir, and tenofovir. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using, especially:

  • any other HIV or AIDS medications;
  • ADHD medication;
  • antibiotic or antifungal medicine;
  • an antidepressant;
  • anti-malaria medication;
  • antiviral medications to treat herpes, HIV, or cytomegalovirus (CMV);
  • asthma or allergy medication;
  • cholesterol-lowering medicine;
  • erectile dysfunction medication (Viagra, Cialis, Levitra);
  • heart or blood pressure medication, heart rhythm medication;
  • insulin or oral diabetes medication;
  • leukemia medication;
  • medicine to treat a psyChiatric disorder;
  • migraine headache medicines;
  • narcotic pain medicine;
  • a sedative;
  • seizure medication; or
  • steroid medication (prednisone and others).
  • This list is not complete and many other drugs can interact with emtricitabine, lopinavir, ritonavir, and tenofovir. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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