Emtricitabine, nelfinavir, and tenofovir

Generic name: Emtricitabine, Nelfinavir, And Tenofovir
Brand names: AccessPak For HIV PEP Expanded With Viracept
Dosage form: oral kit (-)
Drug class: Antiviral combinations

Usage of Emtricitabine, nelfinavir, and tenofovir

Emtricitabine, nelfinavir, and Tenofovir are antiviral drugs that prevent human immunodeficiency virus (HIV) from multiplying in your body.

Emtricitabine, nelfinavir, and tenofovir is a combination medicine used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). emtricitabine, nelfinavir, and tenofovir is not a cure for HIV or AIDS.

This medicine may also be used together with safer-sex practices to reduce the risk of becoming infected with HIV. You must be HIV-negative and an adult to use the medicine for this purpose. Emtricitabine, nelfinavir, and tenofovir may not provide protection from disease in every person.

Emtricitabine, nelfinavir, and tenofovir may also be used for purposes not listed in this medication guide.

Emtricitabine, nelfinavir, and tenofovir side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Mild symptoms of lactic acidosis may worsen over time, and this condition can be fatal. Get emergency medical help if you have: unusual muscle pain, trouble breathing, stomach pain, vomiting, fast/slow or irregular heartbeats, dizziness, feeling cold, or feeling very weak or tired.

Emtricitabine, nelfinavir, and tenofovir may cause serious side effects. Call your doctor at once if you have:

  • kidney problems--little or no urination, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath; or
  • liver problems--nausea, swelling around your midsection, upper stomach pain, unusual tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
  • This medicine affects your immune system, which may cause certain side effects (even weeks or months after you've taken this medicine). Tell your doctor if you have:

  • signs of a new infection--fever, night sweats, swollen glands, cold sores, cough, wheezing, diarrhea, weight loss;
  • trouble speaking or swallowing, problems with balance or eye movement, weakness or prickly feeling; or
  • swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence.
  • Common side effects of emtricitabine, nelfinavir, and tenofovir may include:

  • stomach pain;
  • headache, dizziness, feeling depressed or tired;
  • sleep problems (insomnia), strange dreams;
  • rash;
  • weight loss; or
  • changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Emtricitabine, nelfinavir, and tenofovir

    You should not take this medicine if you are allergic to emtricitabine, nelfinavir, or tenofovir, or if you have severe liver or kidney disease.

    Do not take if you also use other medicines that contain emtricitabine, tenofovir, or lamivudine (Atripla, Complera, Emtriva, Odefsey, Stribild, Triumeq, Viread, and others).

    Do not take this medicine to reduce infection risk if you are HIV-positive, if you have been exposed to HIV within the past month, or if you had any symptoms (such as fever, sore throat, night sweats, swollen glands, diarrhea, body aches).

    If you take emtricitabine, nelfinavir, and tenofovir to reduce your risk of HIV infection: You must have a negative HIV test immediately before you start taking the medicine. An HIV test is also required every 3 months during treatment.

    Many drugs can interact with this medicine and cause dangerous effects. Your doctor may change your treatment plan if you also use:

  • alfuzosin;
  • pimozide;
  • rifampin;
  • sildenafil (Revatio for pulmonary arterial hypertension);
  • St. John's wort;
  • lovastatin or simvastatin;
  • dihydroergotamine, ergotamine, ergonovine, or methylergonovine;
  • amiodarone or quinidine; or
  • oral midazolam, or triazolam.
  • Tell your doctor if you have ever had:

  • a bleeding or blood-clotting disorder such as hemophilia;
  • liver or kidney disease; or
  • hepatitis B infection.
  • You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, if you've taken HIV medication for a long time, or if you are a woman. Ask your doctor about your risk.

    Tell your doctor if you are pregnant, and use your medications properly to control your infection. HIV can be passed to your baby if the virus is not controlled during pregnancy. Your name may be listed on a registry to track any effects of antiviral medicine on the baby.

    Women with HIV or AIDS should not breastfeed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

    This medicine is not approved for use by anyone younger than 2 years old.

    Relate drugs

    Warnings

    You should not take this medicine if you have severe liver or kidney disease. Do not take with other medicines that contain emtricitabine, tenofovir, or lamivudine.

    This medicine is sometimes used to reduce the risk of becoming infected with HIV. You must be HIV-negative to use emtricitabine, nelfinavir, and tenofovir for this purpose.

    Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

    What other drugs will affect Emtricitabine, nelfinavir, and tenofovir

    If you also take didanosine, take it 1 hour before or 2 hours after you take emtricitabine, nelfinavir, and tenofovir.

    Tell your doctor about all your current medicines, especially:

  • antiviral medicine to treat hepatitis C--ledipasvir, sofosbuvir, velpatasvir;
  • other HIV medications--atazanavir, darunavir, didanosine, lopinavir, ritonavir; or
  • some pain or arthritis medicines--aspirin, Tylenol, Advil, and Aleve.
  • This list is not complete and many other drugs may affect emtricitabine, nelfinavir, and tenofovir. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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