Eravacycline

Generic name: Eravacycline
Brand names: Xerava
Dosage form: intravenous powder for injection (100 mg; 50 mg)
Drug class: Tetracyclines

Usage of Eravacycline

Eravacycline is a tetracycline antibiotic that is used to treat serious stomach infections in adults.

Eravacycline may also be used for purposes not listed in this medication guide.

Eravacycline side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Eravacycline may cause serious side effects. Call your doctor at once if you have:

severe stomach pain, diarrhea that is watery or bloody (may occur up to 2 months after your last dose of eravacycline);

severe headaches, dizziness, ringing in your ears, vision problems;

severe pain in your upper stomach spreading to your back, nausea and vomiting; or

signs of a fungal infection--skin itching or crusting, white patches in your mouth, vaginal itching or discharge, problems with your fingernails or toenails.

Common side effects of eravacycline may include:

nausea, vomiting; or

pain, bruising, redness, swelling, burning, or irritation around the IV needle.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Eravacycline

You should not use this medicine if you are allergic to eravacycline or other tetracycline antibiotics such as demeclocycline, doxycycline, minocycline, tetracycline, or tigecycline.

Tell your doctor if you have ever had:

liver disease.

Using eravacycline during the second or third trimester of pregnancy may affect tooth and bone development in the unborn baby. This could cause permanent tooth discoloration later in the baby's life.

Eravacycline can pass into breast milk and may affect bone and tooth development in a nursing infant. Do not breastfeed while you are using eravacycline, and for at least 4 days after your last dose.

Eravacycline is not approved for use by anyone younger than 18 years old. Eravacycline can cause permanent yellowing or graying of the teeth in children.

Relate drugs

How to use Eravacycline

Usual Adult Dose for Intraabdominal Infection:

1 mg/kg IV every 12 hours for 4 to 14 daysUse: For the treatment of complicated intraabdominal infections due to susceptible EscheriChia coli, Klebsiella pneumoniae, Citrobacter freundii, Enterobacter cloacae, K oxytoca, Enterococcus faecalis, E faecium, Staphylococcus aureus, Streptococcus anginosus group, Clostridium perfringens, Bacteroides species, Parabacteroides distasonis

Warnings

You should not use eravacycline if you are allergic to any tetracycline antibiotic.

Using eravacycline during pregnancy may affect tooth and bone development in the unborn baby.

Eravacycline is not approved for use by anyone younger than 18 years old. Eravacycline can cause permanent yellowing or graying of the teeth in children.

What other drugs will affect Eravacycline

Tell your doctor about all your other medicines, especially:

enzalutamide;

mitotane;

rifampin;

St. John's wort; or

a blood thinner--warfarin, Coumadin, Jantoven; or

seizure medicine--Carbamazepine, phenytoin.

This list is not complete. Other drugs may affect eravacycline, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

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