Eraxis

Generic name: Anidulafungin
Drug class: Echinocandins

Usage of Eraxis

Eraxis is an antifungal medication that fights infections caused by fungus.

Eraxis is used to treat candida (yeast) infections in the blood or the stomach in adults and children at least 1 month old.

Eraxis is also used to treat candida infections of the esophagus only in adults.

Eraxis side effects

Get emergency medical help if you have signs of an allergic reaction to Eraxis: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your caregiver right away if you feel light-headed, itchy, warm, tingly, sweaty, or if you have chest tightness or trouble breathing.

Call your doctor at once if you have:

a light-headed feeling, like you might pass out;

trouble breathing;

little or no urination, dark urine, pain or burning when you urinate;

stomach pain and bloating;

easy bruising, unusual bleeding, purple or red spots under the skin;

low potassium - leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling;

low red blood cells (anemia) - pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet; o

(in a baby) severe drowsiness, fussiness, feeding problems, or vomiting.

Common Eraxis side effects may include:

abnormal liver function tests;

low blood sugar (hunger, sweating, irritability, dizziness, feeling shaky);

sore or white patches in your mouth or throat;

low blood pressure, feeling light-headed;

anemia, bruising or bleeding, nosebleed;

fever;

stomach pain, indigestion, nausea, vomiting, diarrhea;

low potassium;

headache, trouble sleeping; or

rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Eraxis

You should not use Eraxis if:

you are allergic to anidulafungin or similar medicines such as caspofungin or micafungin; or

you have hereditary fructose intolerance, a condition that makes it hard for you to digest fructose sugars (such as in certain fruits or juices).

Tell your doctor if you have ever had liver disease.

Tell your doctor if you are pregnant or breastfeeding.

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How to use Eraxis

Usual Adult Dose of Eraxis for Candidemia:

Initial dose: 200 mg IV as a single loading dose on Day 1 Maintenance dose: 100 mg IV once a day thereafter Comments: -Duration of therapy should be based on patient's clinical response. -In general, antifungal therapy should continue for at least 14 days after the last positive culture. Use: For the treatment of candidemia and the following Candida infections: intraabdominal abscess and peritonitis

Usual Adult Dose of Eraxis for Esophageal Candidiasis:

Initial dose: 100 mg IV as a single loading dose on Day 1 Maintenance dose: 50 mg IV once a day thereafter Duration of therapy: At least 14 days and at least 7 days after resolution of symptoms Comments: -Duration of therapy should be based on patient's clinical response. -Due to risk of relapse in HIV-infected patients, suppressive antifungal therapy may be considered after a course of treatment. Use: For the treatment of esophageal candidiasis

Usual Pediatric Dose of Eraxis for Candidemia:

1 month or older: -Initial dose: 3 mg/kg IV as a single loading dose on Day 1 ---Maximum dose: 200 mg/dose -Maintenance dose: 1.5 mg/kg IV once a day thereafter ---Maximum dose: 100 mg/dose Comments: -Overall, antifungal therapy should continue for at least 14 days after the last positive culture. Use: For the treatment of candidemia and the following Candida infections: intraabdominal abscess and peritonitis

Warnings

Use Eraxis for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Eraxis will not treat a viral infection such as the common cold or flu.

Before using Eraxis, tell your doctor if you have liver disease.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What other drugs will affect Eraxis

Other drugs may interact with anidulafungin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

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