Ertugliflozin

Generic name: Ertugliflozin
Brand names: Steglatro
Dosage form: oral tablet (15 mg; 5 mg)
Drug class: SGLT-2 inhibitors

Usage of Ertugliflozin

Ertugliflozin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Ertugliflozin is not for treating type 1 diabetes.

Ertugliflozin may also be used for purposes not listed in this medication guide.

Ertugliflozin side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Seek medical attention right away if you have signs of a genital infection (penis or vagina): burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, not feeling well. These symptoms may get worse quickly.

Ertugliflozin may cause serious side effects. Call your doctor at once if you have:

new pain, tenderness, sores, ulcers, or infections in your legs or feet;

little or no urination;

ketoacidosis (too much acid in the blood)--nausea, vomiting, stomach pain, confusion, unusual drowsiness, or trouble breathing;

low blood sugar--headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery;

dehydration symptoms--dizziness, weakness, feeling light-headed (like you might pass out); or

signs of a bladder infection--pain or burning when you urinate, increased urination, blood in your urine, fever, pain in your pelvis or back.

Some side effects may be more likely to occur in older adults.

Common side effects of ertugliflozin may include:

vaginal odor, discharge, or itching;

redness, itching, swelling, rash, discharge, or pain in the skin around the penis; or

urinating more than usual.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Ertugliflozin

You should not use ertugliflozin if you are allergic to it, or if you have:

severe kidney disease (or if you are on dialysis).

Ertugliflozin may increase your risk of lower leg amputation, especially if you have had a prior amputation, a foot ulcer, heart disease, circulation problems, or nerve damage.

Tell your doctor if you have ever had:

heart problems;

a diabetic foot ulcer or amputation;

circulation problems or nerve problems in your legs or feet;

liver or kidney disease;

bladder infections or other urination problems;

low blood pressure;

diabetic ketoacidosis;

problems with your pancreas, including surgery;

if you drink alcohol often;

if you have a planned surgery;

if you have type 1 diabetes; or

if you are on a low salt diet.

Follow your doctor's instructions about using ertugliflozin if you are pregnant. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester.

You should not use ertugliflozin during the second or third trimester of pregnancy.

You should not breastfeed while using ertugliflozin.

Relate drugs

How to use Ertugliflozin

Usual Adult Dose for Diabetes Type 2:

Initial dose: 5 mg orally once a day in the morning -May increase to 15 mg orally once a day for patients tolerating therapy and requiring additional glycemic controlMaximum dose: 15 mg per dayComments:-Volume depletion should be corrected prior to initiating therapy. -This drug is not recommended for patients with type 1 diabetes mellitus; it may increase the risk of diabetic ketoacidosis in these patients.Use: An adjunct to diet and exercise to improve glycemic control in adults with Type 2 diabetes mellitus.

Warnings

Ertugliflozin may increase your risk of lower leg amputation, especially if you have had a prior amputation, a foot ulcer, heart disease, circulation problems, or nerve damage.

Ertugliflozin can cause serious infections in the penis or vagina. Get medical help right away if you have burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, or if you don't feel well.

What other drugs will affect Ertugliflozin

When you start or stop taking ertugliflozin, your doctor may need to adjust the doses of any other diabetes medicines you use on a regular basis.

Other drugs may affect ertugliflozin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

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