Esbriet
Generic name: Pirfenidone
Drug class:
Miscellaneous uncategorized agents
Usage of Esbriet
Esbriet is used in adults to treat a lung disease called idiopathic pulmonary fibrosis (IPF).
IPF causes scar tissue to form deep within your lungs. The scar tissue thickens and becomes stiff or thick over time, which can make it harder for your lungs to work. Decreased lung function can make it hard for you to breathe. Other medical problems can occur when your brain, heart, and other organs do not get enough oxygen..
The cause of IPF is often unknown, but this condition is a progressive disease that can be fatal..
Esbriet is not a cure for IPF, but this medicine may slow the progress of this disease..
Esbriet belongs to a class of medications called pyridones. Pirfenidone works by blocking the action of a certain natural substance in the body that is involved in causing fibrosis.
Esbriet side effects
Get emergency medical help if you have signs of an allergic reaction to Esbriet (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.
Esbriet may cause serious side effects. Call your doctor at once if you have:
Common Esbriet side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Esbriet
To make sure Esbriet is safe for you, tell your doctor if you have ever had:
It is not known if pirfenidone will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
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How to use Esbriet
Usual Adult Dose for Idiopathic Pulmonary Fibrosis:
Initial dose: -Days 1 to 7: 267 mg (one capsule) orally three times a day -Days 8 to 14: 534 mg (two capsules) orally three times a day Maintenance/Maximum dose (Day 15 onward): 801 mg (three capsules) orally three times a day Comments: -Take with food to reduce nausea and dizziness. -Doses should be taken at the same time each day. Use: Idiopathic pulmonary fibrosis (IPF)
Warnings
Tell your doctor and pharmacist if you are allergic to pirfenidone, any other medications, or any of the ingredients in Esbriet capsules or tablets.
Tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take while taking Esbriet. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
What other drugs will affect Esbriet
Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.
Other drugs may interact with pirfenidone, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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