Esterified estrogens and methyltestosterone
Generic name: Esterified Estrogens And Methyltestosterone
Dosage form: oral tablet (0.625 mg-1.25 mg; 1.25 mg-2.5 mg)
Drug class:
Sex hormone combinations
Usage of Esterified estrogens and methyltestosterone
Esterified estrogens are female sex hormones produced by the ovaries.
Methyltestosterone is a sex hormone that is produced in a man's testicles. Small amounts of testosterone are also produced in a woman's ovaries and adrenal system.
Esterified estrogens and methyltestosterone is a combination medicine used to treat symptoms of menopause such as hot flashes or night sweats. esterified estrogens and methyltestosterone is usually given only short-term (such as 3 to 6 months).
Esterified estrogens and methyltestosterone may also be used for purposes not listed in this medication guide.
Esterified estrogens and methyltestosterone side effects
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Esterified estrogens and methyltestosterone may cause serious side effects. Call your doctor at once if you have:
Methyltestosterone can cause symptoms of male features in a woman taking this medicine. Call your doctor if you develop enlarged genitals, male-pattern baldness, excessive body hair growth, increased acne, irregular menstrual periods, or any signs of male characteristics.
Common side effects of esterified estrogens and methyltestosterone may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Esterified estrogens and methyltestosterone
You should not use esterified estrogens and methyltestosterone if you have:
Do not use this medicine if you are pregnant. Tell your doctor right away if you become pregnant during treatment.
Using this medicine can increase your risk of blood clots, stroke, or heart attack. You are even more at risk if you have high blood pressure, diabetes, high cholesterol, if you are overweight, or if you smoke.
Esterified estrogens and methyltestosterone should not be used to prevent heart disease or stroke because this medicine may actually increase your risk of developing these conditions.
Tell your doctor if you have ever had:
Using this medicine may increase your risk of cancer of the breast, uterus, vagina, or liver. Talk with your doctor about this risk.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
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How to use Esterified estrogens and methyltestosterone
Usual Adult Dose for Postmenopausal Symptoms:
Esterified estrogens-medroxyprogesterone 1.25 mg-2.5 mg oral tablets: one tablet orally once a day orEsterified estrogens-medroxyprogesterone 0.625 mg-1.25 mg oral tablets: one or two tablets orally once a day Comments: -Administration should be cyclic (e.g., three weeks on and one week off); women with a uterus should receive a progestin to reduce the risk of endometrial cancer. -This drug should be used at the lowest dose that will control symptoms for the shortest duration consistent with treatment goals; attempts to discontinue or taper medication should be made at 3 to 6 month intervals. -There is no evidence that estrogens are effective for nervous symptoms or depression without associated vasomotor symptoms, and they should not be used to treat such conditions. Use: For treatment of moderate to severe vasomotor symptoms associated with the menopause in patients not improved by estrogen alone.
Warnings
You should not use esterified estrogens and methyltestosterone if you have: undiagnosed vaginal bleeding, severe liver disease, if you will have major surgery, or if you have ever had a stroke, a blood clot, or cancer of the breast, uterus/cervix, or vagina.
Do not use if you are pregnant or breastfeeding.
Estrogens may increase your risk of developing a condition that may lead to uterine cancer. Report any unusual vaginal bleeding right away.
Using this medicine can increase your risk of blood clots, stroke, heart attack, or cancer of the breast, uterus, vagina, or liver. Estrogens should not be used to prevent heart disease.
What other drugs will affect Esterified estrogens and methyltestosterone
Tell your doctor about all your other medicines, especially:
This list is not complete. Other drugs may affect esterified estrogens and methyltestosterone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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