Evista

Generic name: Raloxifene

Usage of Evista

Evista affects the cycle of bone formation and breakdown in the body, and reduces loss of bone tissue.

Evista is used to treat or prevent osteoporosis in postmenopausal women. Evista is also used to reduce the risk of invasive breast cancer in postmenopausal women who have osteoporosis or who are otherwise at risk of invasive breast cancer.

Evista is not a cancer medication and will not treat breast cancer.

Evista side effects

Get emergency medical help if you have signs of an allergic reaction to Evista: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • swelling, tenderness, or other changes in your breasts;
  • signs of a stroke - sudden numbness or weakness (especially on one side of the body), slurred speech, vision problems;
  • signs of a blood clot in the lung - chest pain, trouble breathing, coughing up blood; or
  • signs of a blood clot deep in the body - swelling, warmth, or redness in an arm or leg.
  • Common Evista side effects may include:

  • hot flashes;
  • leg cramps;
  • swelling in your hands, feet, or ankles;
  • joint pain;
  • flu symptoms; or
  • increased sweating.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Evista

    This medicine may increase your risk of a blood clot in your leg, your lung, or your eye. You should not take Evista if you have ever had this type of blood clot.

    This medicine is for use only in women who can no longer get pregnant. Raloxifene can harm an unborn baby. Do not use if you are pregnant or may become pregnant.

    Do not breastfeed while taking Evista.

    Raloxifene can increase your risk of a stroke, which can be fatal. Tell your doctor if you have ever had:

  • heart problems, irregular heartbeats;
  • a heart attack or stroke, including "mini-stroke";
  • high blood pressure;
  • cancer; or
  • if you smoke.
  • To make sure Evista is safe for you, tell your doctor if you have ever had:

  • a blood clot;
  • high triglycerides caused by using estrogen;
  • liver or kidney disease;
  • endometriosis;
  • abnormal vaginal bleeding; or
  • if you have not gone through menopause.
  • How to use Evista

    Usual Adult Dose for Osteoporosis:

    60 mg orally per day Comments: -For treatment or prevention of osteoporosis, advise patients to add supplemental calcium and/or vitamin D if daily intake is inadequate. -When this drug is used to reduce the risk of invasive breast cancer, the optimum duration of treatment is not known. Uses: -Treatment and prevention of osteoporosis in postmenopausal women. -Reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and/or at high risk of invasive breast cancer.

    Usual Adult Dose for Prevention of Osteoporosis:

    60 mg orally per day Comments: -For treatment or prevention of osteoporosis, advise patients to add supplemental calcium and/or vitamin D if daily intake is inadequate. -When this drug is used to reduce the risk of invasive breast cancer, the optimum duration of treatment is not known. Uses: -Treatment and prevention of osteoporosis in postmenopausal women. -Reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and/or at high risk of invasive breast cancer.

    Usual Adult Dose for Prevention of Breast Cancer:

    60 mg orally per day Comments: -For treatment or prevention of osteoporosis, advise patients to add supplemental calcium and/or vitamin D if daily intake is inadequate. -When this drug is used to reduce the risk of invasive breast cancer, the optimum duration of treatment is not known. Uses: -Treatment and prevention of osteoporosis in postmenopausal women. -Reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and/or at high risk of invasive breast cancer.

    Warnings

    Taking Evista may increase your risk of a blood clot in your leg, your lung, or your eye. You should not take this medicine if you have ever had a blood clot.

    Evista can also increase your risk of a stroke, which can be fatal. This risk is highest if you have coronary heart disease or certain risk factors (such as diabetes, smoking, being overweight, having high blood pressure or high cholesterol, or having a family history of coronary artery disease).

    Although this medicine is for use only in postmenopausal women, you should not take Evista if you are pregnant or breastfeeding.

    What other drugs will affect Evista

    Tell your doctor about all your other medicines, especially:

  • cholestyramine;
  • warfarin (Coumadin, Jantoven); or
  • birth control pills or hormone replacement therapy.
  • This list is not complete. Other drugs may interact with raloxifene, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

    Disclaimer

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