Fasenra

Generic name: Benralizumab
Drug class: Interleukin inhibitors

Usage of Fasenra

Fasenra is a monoclonal antibody that affects the actions of the body's immune system. Benralizumab works by reducing levels of eosinophils, a certain type of white blood cell that may contribute to the symptoms of asthma.

Fasenra injection is a prescription medicine used together with other asthma medicines to help control severe asthma in adults and children who are at least 12 years old.

Fasenra is for people whose asthma is not well controlled with other medications.

Fasenra side effects

Get emergency medical help if you have signs of an allergic Reaction to Fasenra: hives, rash; difficult breathing, feeling light-headed; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • new or worsening asthma symptoms.

    • Common Fasenra side effects may include:

  • sore throat; or
  • headache.

    • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Fasenra

    You should not be treated with Fasenra if you are allergic to benralizumab.

    Tell your doctor if you have ever had:

  • a parasite infection (such as roundworms or tapeworms); or
  • if you use an oral or inhaled steroid medication.

    • Follow your doctor's instructions about receiving this medicine if you are pregnant. Not treating asthma during pregnancy could harm both mother and baby. Tell your doctor if you are pregnant or plan to become pregnant.

    It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.

    Fasenra should not be given to a child younger than 12 years old.

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    How to use Fasenra

    Usual Adult Dose for Asthma:

    30 mg suBCUTAneously once every 4 weeks for the first 3 doses, then once every 8 weeks thereafter Comments: -This drug should be injected into the upper arm (for caregiver administration only), thigh, or abdomen. Use: For add-on maintenance therapy of patients with severe asthma with an eosinophilic phenotype

    Usual Pediatric Dose for Asthma:

    12 years and older: 30 mg subcutaneously once every 4 weeks for the first 3 doses, then once every 8 weeks thereafter Comments: -This drug should be injected into the upper arm (for caregiver administration only), thigh, or abdomen. Use: For add-on maintenance therapy of patients 12 years and older with severe asthma with an eosinophilic phenotype

    Warnings

    Before you receive Fasenra, tell your doctor about all your medical conditions or allergies, all medicines you use, and if you are pregnant or breast-feeding.

    What other drugs will affect Fasenra

    Other drugs may interact with benralizumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

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