Fenoprofen

Generic name: Fenoprofen
Drug class: Nonsteroidal anti-inflammatory drugs

Usage of Fenoprofen

Fenoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat mild to moderate pain, osteoarthritis, or rheumatoid arthritis.

Fenoprofen may also be used for purposes not listed in this medication guide.

Fenoprofen side effects

Get emergency medical help if you have signs of an allergic reaction (hives, runny or stuffy nose, wheezing, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, swelling in your legs, feeling short of breath.

Fenoprofen may cause serious side effects. Stop using fenoprofen and call your doctor at once if you have:

  • changes in your vision;
  • any skin rash, no matter how mild;
  • shortness of breath (even with mild exertion);
  • swelling or rapid weight gain;
  • signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
  • liver problems--nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • kidney problems--little or no urination, swelling in your feet or ankles, feeling tired; or
  • low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed, cold hands and feet.
  • Common side effects of fenoprofen may include:

  • nausea, vomiting, stomach pain, indigestion;
  • diarrhea, constipation;
  • headache, dizziness, drowsiness, tiredness;
  • feeling nervous;
  • itching, sweating; or
  • ringing in your ears.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Fenoprofen

    Fenoprofen can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

    Fenoprofen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using fenoprofen, especially in older adults.

    You should not use fenoprofen if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.

    Tell your doctor if you have ever had:

  • heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke;
  • a heart attack, stroke, or blood clot;
  • stomach ulcers or bleeding;
  • asthma;
  • fluid retention;
  • liver or kidney disease; or
  • if you take aspirin to prevent heart attack or stroke.
  • If you are pregnant, you should not take fenoprofen unless your doctor tells you to. Taking an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.

    You should not breastfeed while using fenoprofen.

    Fenoprofen is not approved for use by anyone younger than 18 years old.

    Relate drugs

    How to use Fenoprofen

    Usual Adult Dose for Osteoarthritis:

    400 mg to 600 mg orally 3 or 4 times a day-Maximum dose: 3200 mg/dayComments:-Dose adjustments should be made following initiation of therapy or during exacerbations of the disease.-Patients with rheumatoid arthritis usually require larger doses than those with osteoarthritis; the lowest effective dose that yields acceptable control for either condition should be employed.Use: For the relief of signs and symptoms of osteoarthritis and rheumatoid arthritis

    Usual Adult Dose for Rheumatoid Arthritis:

    400 mg to 600 mg orally 3 or 4 times a day-Maximum dose: 3200 mg/dayComments:-Dose adjustments should be made following initiation of therapy or during exacerbations of the disease.-Patients with rheumatoid arthritis usually require larger doses than those with osteoarthritis; the lowest effective dose that yields acceptable control for either condition should be employed.Use: For the relief of signs and symptoms of osteoarthritis and rheumatoid arthritis

    Usual Adult Dose for Pain:

    200 mg orally every 4 to 6 hours as neededUse: For the relief of mild to moderate pain

    Warnings

    Fenoprofen can increase your risk of fatal heart attack or stroke. Do not use fenoprofen just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Fenoprofen may also cause stomach or intestinal bleeding, which can be fatal.

    What other drugs will affect Fenoprofen

    Ask your doctor before using fenoprofen if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily.

    Tell your doctor about all your other medicines, especially:

  • cyclosporine;
  • lithium;
  • methotrexate;
  • a blood thinner (warfarin, Coumadin, Jantoven);
  • heart or blood pressure medication, including a diuretic or "water pill";
  • oral diabetes medicine;
  • seizure medicine (especially phenobarbital or phenytoin);
  • steroid medicine (such as prednisone); or
  • a sulfa drug.
  • This list is not complete. Other drugs may affect fenoprofen, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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