Ferric citrate

Generic name: Ferric Citrate
Brand names: Auryxia
Dosage form: oral tablet (210 mg)
Drug class: Phosphate binders

Usage of Ferric citrate

Ferric citrate contains iron that binds to the phosphates you take in through food, which helps your body absorb fewer phosphates. This can lower the amount of phosphorus (a mineral) in your blood.

Ferric citrate is used to control phosphorus levels in adults with chronic kidney disease who are on dialysis.

Ferric citrate is also used to treat iron deficiency anemia in adults with chronic kidney disease who are not on dialysis.

Ferric citrate may also be used for purposes not listed in this medication guide.

Ferric citrate side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Ferric citrate may cause serious side effects. Call your doctor at once if you have:

severe stomach problems (pain, vomiting, diarrhea); or

high potassium--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement.

Common side effects of ferric citrate may include:

diarrhea, constipation;

darker color in your bowel movements;

nausea, vomiting, stomach pain; or

cough.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Ferric citrate

You should not use ferric citrate if you are allergic to it, or if you have:

iron overload disorder (hemochromatosis).

Tell your doctor if you have ever had:

liver disease;

a stomach or intestinal disorder;

stomach bleeding; or

stomach or intestinal surgery.

It is not known whether this medicine will harm an unborn baby. An overdose of iron can cause miscarriage, birth defects, or pregnancy-related diabetes. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.

Your dose needs may be different during pregnancy or while you are nursing.

This medicine is not approved for use by anyone younger than 18 years old.

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How to use Ferric citrate

Usual Adult Dose for Hyperphosphatemia of Renal Failure:

Each tablet contains ferric iron 210 mg equivalent to ferric citrate 1 gInitial dose: 2 tablets orally 3 times a day with meals-Adjust dose in increments/decrements of 1 to 2 tablets per day per week or longer intervals to maintain serum phosphorous at target levelsAverage dose: 8 to 9 tablets per dayMaximum dose: 12 tablets per dayComments:-Monitor serum phosphorous and titrate dose accordingly.-Tablets should not be chewed or crushed because it may cause discoloration of mouth and teeth.Use: Control of serum phosphorous levels in patients with chronic kidney disease on dialysis.

Usual Adult Dose for Anemia Associated with Chronic Renal Failure:

Each tablet contains ferric iron 210 mg equivalent to ferric citrate 1 gInitial dose: 1 tablet orally 3 times a day with meals-Adjust dose as needed to achieve and maintain target hemoglobin levelsAverage dose: 5 tablets per dayMaximum dose: 12 tablets per dayComments:-Tablets should not be chewed or crushed because it may cause discoloration of mouth and teeth.Use: Treatment of iron deficiency anemia in patients with chronic kidney disease not on dialysis.

Usual Adult Dose for Iron Deficiency Anemia:

Warnings

Keep ferric citrate out of the reach of children. An accidental overdose of ferric citrate by a child can be fatal.

What other drugs will affect Ferric citrate

If you take any of the following medicines, take them separately from your dose of ferric citrate:

An antibiotic called doxycycline: take ferric citrate at least 1 hour before you take ferric citrate.

An antibiotic called ciprofloxacin: take it at least 2 hours before or 2 hours after you take ferric citrate.

Other drugs may affect ferric citrate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

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