Ferumoxytol

Generic name: Ferumoxytol
Brand names: Feraheme
Dosage form: intravenous solution (30 mg/mL)
Drug class: Iron products

Usage of Ferumoxytol

Ferumoxytol is an iron replacement product that is used in adults used to treat iron deficiency anemia (IDA), which is low red blood cells caused by a lack of iron in the body.

Ferumoxytol is given to adults with IDA and chronic kidney disease, or to adults with IDA when iron taken by mouth is not effective.

Ferumoxytol may also be used for purposes not listed in this medication guide.

Ferumoxytol side effects

Get emergency medical help if you have signs of an allergic reaction: hives, itching; wheezing, difficult breathing; a light-headed feeling (like you might pass out);swelling of your face, lips, tongue, or throat.

Ferumoxytol can cause severe or fatal allergic reactions, even if you have used ferumoxytol before without any reaction. Watch for signs of allergic reaction for at least 30 minutes after your injection.

Ferumoxytol may cause serious side effects. Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • severe or ongoing vomiting or diarrhea;
  • a seizure;
  • kidney problems--swelling, urinating less, feeling tired or short of breath; or
  • heart problems--chest pain, fast or pounding heartbeats, rapid weight gain, feeling short of breath.
  • Common side effects of ferumoxytol may include:

  • headache, dizziness;
  • diarrhea, constipation;
  • nausea; or
  • swelling in your arms, hands, legs, or feet.
  • Before taking Ferumoxytol

    You should not use ferumoxytol if you are allergic to it, or if:

  • you've had an allergic reaction to iron injected into a vein.
  • Tell your doctor if you have ever had:

  • iron overload syndrome;
  • any drug allergies; or
  • low blood pressure.
  • Tell your doctor if you are pregnant or plan to become pregnant. It is not known if ferumoxytol will harm an unborn baby, but ferumoxytol may cause severe reactions in the mother that could affect the baby's heartbeat.

    Having iron deficiency anemia during pregnancy may increase the risk of premature birth or low birth weight. The benefit of treating this condition with ferumoxytol may outweigh any risks to the baby.

    Ask a doctor if it is safe to breastfeed while using this medicine.

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    How to use Ferumoxytol

    Usual Adult Dose for Iron Deficiency Anemia:

    Initial dose: 510 mg, IV, over at least 15 minutes Second dose: 510 mg, IV, over at least 15 minutes, 3 to 8 days after the initial doseComments:-The patient should be reclined or semi-reclined during administration.-Evaluate hematologic response at least one month after the second infusion.-May be readministered for persistent or recurrent iron deficiency anemia.Use: Iron deficiency anemia in adult patients with chronic kidney disease.

    Warnings

    Ferumoxytol can cause severe or fatal allergic reactions, even if you have used this medicine before without any reaction. Get emergency medical help if you have hives, itching, wheezing, trouble breathing, swelling in your face or throat, or feeling like you might pass out. Watch for signs of allergic reaction for at least 30 minutes after your injection.

    What other drugs will affect Ferumoxytol

    Ferumoxytol can make it harder for your body to absorb iron medicines you take by mouth.

    Other drugs may affect ferumoxytol, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

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