Fezolinetant

Generic name: Fezolinetant
Brand names: Veozah
Dosage form: oral tablet (45 mg)
Drug class: Miscellaneous central nervous system agents

Usage of Fezolinetant

Fezolinetant is used in menopausal adult women to treat symptoms of "hot flashes" and night sweats.

Fezolinetant may also be used for purposes not listed in this medication guide.

Fezolinetant side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Fezolinetant may cause serious side effects. Call your doctor at once if you have:

  • liver problems--loss of appetite, nausea, vomiting, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
  • Common side effects of fezolinetant may include:

  • abnormal liver function tests;
  • stomach or back pain;
  • diarrhea;
  • sleep problems (insomnia); or
  • hot flashes or hot flush.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Fezolinetant

    You should not use fezolinetant if you have:

  • cirrhosis; or
  • kidney problems or end-stage kidney disease.
  • Some drugs should not be used with fezolinetant. Your treatment plan may change if you also:

  • take certain medicines such as cimetidine, fluvoxamine, and mexiletine.
  • There may be other reasons you should not use fezolinetant in combination with certain medicines. Ask your doctor if you are not sure.

    Tell your doctor if you have other medical conditions.

    Tell your doctor if you are pregnant or breastfeeding.

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    How to use Fezolinetant

    Usual Adult Dose for Postmenopausal Symptoms:

    Recommended dose: 45 mg orally once a day Comments:-Evaluate liver function prior to treatment initiation and periodically as recommended. Use: For the treatment of moderate to severe vasomotor symptoms due to menopause

    Warnings

    Tell your doctor about all your other medicines. Some drugs should not be used with fezolinetant.

    What other drugs will affect Fezolinetant

    Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.

    Other drugs may affect fezolinetant, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

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