Firazyr

Generic name: Icatibant
Drug class: Hereditary angioedema agents

Usage of Firazyr

Firazyr is used to treat attacks of hereditary angioedema (an immune system disorder) in adults.

Firazyr is not a cure for hereditary angioedema.

Firazyr may also be used for purposes not listed in this medication guide.

Firazyr side effects

Get emergency medical help if you have signs of an allergic reaction to Firazyr: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

An allergic reaction to icatibant is unlikely to occur, but could cause symptoms that are very similar to the signs of hereditary angioedema.

Common Firazyr side effects may include:

  • pain, numbness, bruising, redness, swelling, warmth, burning, irritation, hives, itching, or a feeling of pressure where the injection was given;
  • drowsiness, tiredness;
  • fever;
  • headache, dizziness;
  • abnormal liver function tests;
  • nausea; or
  • rash.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Firazyr

    Before using Firazyr tell your doctor about all your medical conditions or allergies, all medicines you use, and if you are pregnant or breastfeeding.

    Older adults may be more sensitive to the effects of this medicine.

    Firazyr is not approved for use by anyone younger than 18 years old.

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    How to use Firazyr

    Usual Adult Dose for Hereditary Angioedema:

    30 mg suBCutaneously once, in the abdominal area; may repeat every 6 hours if response is inadequate or symptoms recur. Maximum dose: 90 mg/day

    Warnings

    You should not use Firazyr if you are allergic to icatibant.

    To make sure you can safely use this medicine, tell your doctor about all of your medical conditions, if you use heart or blood pressure medications, and if you are pregnant or breast-feeding.

    Get emergency medical help if you have any swelling of your tongue or throat during an angioedema attack.

    An allergic reaction to icatibant can cause symptoms that are very similar to the signs of hereditary angioedema, including: hives, trouble breathing, or swelling of your face, lips, tongue, or throat.

    Do not use more than three Firazyr injections within a 24-hour period. Call your doctor if your symptoms do not improve, or if they get worse after using this medication.

    What other drugs will affect Firazyr

    Tell your doctor about all your other medicines, especially heart or blood pressure medication.

    Other drugs may interact with icatibant, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

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