Flecainide

Generic name: Flecainide
Brand names: Tambocor
Dosage form: oral tablet (100 mg; 150 mg; 50 mg)
Drug class: Group I antiarrhythmics

Usage of Flecainide

Flecainide is a Class IC anti-arrhythmic that is used in certain situations to prevent serious heart rhythm disorders.

Flecainide may also be used for purposes not listed in this medication guide.

Flecainide side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Flecainide may cause serious side effects. Call your doctor at once if you have:

  • fast or pounding heartbeats;
  • fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);
  • slow heart rate, weak pulse, slow breathing (breathing may stop);
  • feeling short of breath;
  • swelling, rapid weight gain;
  • pale skin, easy bruising or bleeding, unusual weakness;
  • fever, flu-like symptoms; or
  • jaundice (yellowing of the skin or eyes).

    • Common side effects of flecainide may include:

  • dizziness;
  • vision problems;
  • trouble breathing;
  • headache;
  • nausea; or
  • feeling weak or tired.

    • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Flecainide

    You should not use flecainide if you are allergic to it, or if:

  • you have a serious heart condition such as bundle branch block or AV block (unless you have a pacemaker); or
  • your heart cannot pump blood properly.

    • Tell your doctor if you have ever had:

  • a heart attack;
  • chronic atrial fibrillation, or "AFib";
  • congestive heart failure;
  • a heart condition called "sick sinus syndrome";
  • an electrolyte imbalance (such as low levels of potassium or magnesium in your blood); or
  • liver disease.

    • It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

    It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

    Relate drugs

    How to use Flecainide

    Usual Adult Dose for Ventricular Tachycardia:

    Initial dose: 100 mg orally every 12 hours. Maintenance dose: May be increased in increments of 50 mg bid every 4 days until efficacy is achieved. Most patients with SUSTAINED VT do not require more than 150 mg every 12 hours (300 mg/day), and the maximum dose recommended is 400 mg/day.

    Usual Adult Dose for Atrial Fibrillation:

    Initial dose: 50 mg orally every 12 hours. Maintenance dose: May be increased in increments of 50 mg bid every 4 days until efficacy is achieved.

    Usual Adult Dose for Atrial Flutter:

    Initial dose: 50 mg orally every 12 hours. Maintenance dose: May be increased in increments of 50 mg bid every 4 days until efficacy is achieved.

    Usual Adult Dose for Wolff-Parkinson-White Syndrome:

    Initial dose: 50 mg orally every 12 hours. Maintenance dose: May be increased in increments of 50 mg bid every 4 days until efficacy is achieved.

    Usual Adult Dose for Paroxysmal Supraventricular Tachycardia:

    Initial dose: 50 mg orally every 12 hours. Maintenance dose: May be increased in increments of 50 mg bid every 4 days until efficacy is achieved.

    Usual Pediatric Dose for Supraventricular Tachycardia:

    less than 1 month:Supraventricular tachycardia: Limited data available: Initial: 2 mg/kg/day orally divided every 12 hours; titrate to clinical response, monitor serum concentration; mean dose required to suppress SVT: 3.35 ± 1.35 mg/kg/day in 17 neonates (n=20 treated neonates; mean PNA: 11.5 days; mean GA: 36.8 weeks; mean birthweight: 2.8 kg); study did not report resultant serum concentrations.1 month or older:Initial: 1 to 3 mg/kg/day orally or 50 to 100 mg/m2/day orally in 3 divided doses; usual: 3 to 6 mg/kg/day or 100 to 150 mg/m2/day in 3 divided doses; up to 8 mg/kg/day or 200 mg/m2/day for uncontrolled patients with subtherapeutic levels; higher doses have been reported, however they may be associated with an increased risk of proarrhythmias; a review of world literature reports the average effective dose to be 4 mg/kg/day or 140 mg/m2/day.

    Warnings

    You should not use flecainide if you have a serious heart condition such as bundle branch block or AV block (without a pacemaker), or if your heart cannot pump blood properly.

    You may receive your first dose in a hospital or clinic setting to quickly treat any serious side effects.

    What other drugs will affect Flecainide

    Tell your doctor about all your other medicines, especially:

  • digoxin;
  • a diuretic or "water pill";
  • a beta-blocker (atenolol, metoprolol, propranolol, sotalol, and others);
  • other heart medications such as amiodarone, diltiazem, disopyramide, nifedipine, quinidine, or verapamil; or
  • seizure medication.

    • This list is not complete. Other drugs may affect flecainide, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

    Disclaimer

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    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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