Fluocinolone, hydroquinone, and tretinoin topical

Generic name: Fluocinolone, Hydroquinone, And Tretinoin Topical
Brand names: Tri-Luma
Dosage form: topical cream (0.01%-4%-0.05%)
Drug class: Topical depigmenting agents

Usage of Fluocinolone, hydroquinone, and tretinoin topical

Fluocinolone is a steroid that reduces inflammation or swelling.

Hydroquinone is a skin bleaching agent.

Tretinoin is a form of vitamin A that helps the skin to renew itself more quickly.

Fluocinolone, hydroquinone, and tretinoin topical (for use on the skin) is a combination medicine used to treat melasma (dark skin patches) on the face.

Fluocinolone, hydroquinone, and tretinoin topical may also be used for purposes not listed in this medication guide.

Fluocinolone, hydroquinone, and tretinoin topical side effects

Get emergency medical help if you have signs of an allergic reaction: hives, severe itching; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using fluocinolone, hydroquinone, and tretinoin topical and call your doctor at once if you have:

  • darkening or discoloration of treated skin;
  • irritation of your eyes, nose, or mouth;
  • severe skin redness, itching, peeling, blistering, or crusting;
  • severe burning or swelling of the skin; or
  • possible signs of absorbing fluocinolone through your skin--worsening tiredness or muscle weakness; loss of appetite, diarrhea; weight loss or weight gain (especially in your face or your upper back and torso); slow wound healing, thinning skin, increased body hair; changes in sexual function; depression, anxiety, feeling irritable.
  • Common side effects of fluocinolone, hydroquinone, and tretinoin topical may include:

  • acne; or
  • mild redness, burning, itching, dryness, or peeling of your skin.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Fluocinolone, hydroquinone, and tretinoin topical

    You should not use fluocinolone, hydroquinone, and tretinoin topical if you are allergic to fluocinolone, hydroquinone, or tretinoin.

    To make sure this medicine is safe for you, tell your doctor if you have:

  • asthma; or
  • a sulfite allergy.
  • Using fluocinolone, hydroquinone, and tretinoin topical during pregnancy could harm the unborn baby. Tell your doctor if you are pregnant or if you become pregnant while using this medicine.

    The pill form of tretinoin is known to cause birth defects. Although your skin does not absorb as much tretinoin as if you were taking the medicine by mouth, it may be best not to use fluocinolone, hydroquinone, and tretinoin topical if you are pregnant. Talk to your doctor first.

    Hormonal contraception (birth control pills, injections, implants, skin patches, and vaginal rings) can cause melasma to get worse. Ask your doctor about using a non hormonal birth control (condom, diaphragm with spermicide) instead.

    It is not known whether fluocinolone, hydroquinone, and tretinoin topical passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

    This medicine is not approved for use by anyone younger than 18 years old.

    Relate drugs

    How to use Fluocinolone, hydroquinone, and tretinoin topical

    Usual Adult Dose for Melasma:

    Apply a thin layer to the affected area(s) once a day, at least 30 minutes before bedtimeComments:-The affected area(s) should be washed with a mild cleanser and dried before application of this drug.-Patients should extend application of the cream to approximately 1/2 inch of normal appearing skin (surrounding each lesion), and then the cream should rubbed lightly and uniformly into the skin.-Treatment should be discontinued once control is achieved.Use: Short-term treatment of moderate to severe melasma of the face, in combination with sun avoidance measures (e.g., sunscreen use)

    Warnings

    Avoid exposure to sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

    What other drugs will affect Fluocinolone, hydroquinone, and tretinoin topical

    It is not likely that other drugs you take orally or inject will have an effect on topically applied fluocinolone, hydroquinone, and tretinoin. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

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