Fosnetupitant and palonosetron injection

Generic name: Fosnetupitant And Palonosetron (injection)
Dosage form: intravenous powder for injection (235 mg-0.25 mg)
Drug class: Miscellaneous antiemetics

Usage of Fosnetupitant and palonosetron injection

Fosnetupitant and palonosetron is a combination medicine used to help prevent nausea and vomiting caused by chemotherapy. fosnetupitant and palonosetron is given together with a steroid called dexamethasone.

Fosnetupitant and palonosetron helps prevent nausea and vomiting that occurs both during chemotherapy and later on (delayed nausea and vomiting).

Fosnetupitant and palonosetron may also be used for purposes not listed in this medication guide.

Fosnetupitant and palonosetron injection side effects

Get emergency medical help if you have signs of an allergic reaction: hives; chest pain, difficult breathing; swelling of your face, lips, tongue, or throat.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Common side effects of fosnetupitant and palonosetron may include:

headache;

feeling weak or tired;

skin redness; or

upset stomach, constipation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Fosnetupitant and palonosetron injection

Fosnetupitant and palonosetron may harm an unborn baby. Tell your doctor if you become pregnant.

Tell your doctor if you have ever had:

liver or kidney disease; or

an allergic reaction to a medicine for nausea or vomiting, such as dolasetron (Anzemet), ondansetron (Zofran), or palonosetron (Aloxi).

Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, or serious infections. These medicines may interact with fosnetupitant and palonosetron and cause a serious condition called serotonin syndrome.

You should not breast-feed while using fosnetupitant and palonosetron.

Fosnetupitant and palonosetron is not approved for use by anyone younger than 18 years old.

Relate drugs

How to use Fosnetupitant and palonosetron injection

Usual Adult Dose for Nausea/Vomiting -- Chemotherapy Induced:

Fosnetupitant 235 mg-palonosetron 0.25 mg via IV infusion over 30 minutes ONCE, starting 30 minutes before chemotherapy on Day 1ADDITIONAL MEDICATIONS:Highly Emetogenic Cancer Chemotherapy, Including Cisplatin-Based Chemotherapy:-Day 1: Dexamethasone 12 mg orally 30 minutes prior to chemotherapy-Days 2 to 4: Dexamethasone 8 mg orally once a dayUse: In combination with dexamethasone for the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What other drugs will affect Fosnetupitant and palonosetron injection

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Many drugs can affect fosnetupitant and palonosetron. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.