Fostamatinib

Generic name: Fostamatinib
Brand names: Tavalisse
Dosage form: oral tablet (100 mg; 150 mg)
Drug class: Miscellaneous coagulation modifiers

Usage of Fostamatinib

Fostamatinib is used to treat chronic immune thrombocytopenia, a bleeding condition caused by a lack of platelets in the blood. fostamatinib is given after other treatments have failed.

Fostamatinib may also be used for purposes not listed in this medication guide.

Fostamatinib side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Fostamatinib may cause serious side effects. Call your doctor at once if you have:

severe diarrhea;

stomach pain (upper right side);

dark urine, jaundice (yellowing of the skin or eyes);

headaches, chest pain, shortness of breath; or

fever, sore throat, or other signs of infection.

Your fostamatinib doses may be delayed or permanently discontinued if you have certain side effects.

Common side effects of fostamatinib may include:

increased blood pressure;

diarrhea, nausea, stomach pain;

abnormal liver function tests;

chest pain;

dizziness, tiredness;

rash; or

cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Fostamatinib

Fostamatinib is not approved for use by anyone younger than 18 years old.

Tell your doctor if you have ever had:

high blood pressure; or

liver problems.

Do not use fostamatinib if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using fostamatinib and for at least 1 month after your last dose.

Do not breast-feed while using this medicine, and for at least 1 month after your last dose.

Relate drugs

How to use Fostamatinib

Usual Adult Dose for Thrombocytopenia:

100 mg orally 2 times a day; after a month, if platelet count has not increased to at least 50 x 10(9)/L, increase to 150 mg orally 2 times a dayComments:-This drug may be taken with or without food. -In the case of a missed dose, instruct patients to take their next dose at its regularly scheduled time.-Use the lowest dose to achieve and maintain a platelet count at least 50 x 10(9)/L to reduce the risk of bleeding.Use: For the treatment of thrombocytopenia in adult patients with chronic immune thrombocytopenia (ITP) who have had an insufficient response to a previous treatment

Warnings

Fostamatinib can raise your blood pressure, sometimes to dangerous levels. Fostamatinib may also cause liver problems, severe diarrhea, and infections.

Call your doctor if you have: headaches, chest pain, shortness of breath, severe diarrhea, stomach pain, fever, or sore throat.

What other drugs will affect Fostamatinib

Other drugs may affect fostamatinib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

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