Fostemsavir

Generic name: Fostemsavir
Brand names: Rukobia
Dosage form: oral tablet, extended release (600 mg)
Drug class: Miscellaneous antivirals

Usage of Fostemsavir

Fostemsavir is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body.

Fostemsavir is used with other antiviral drugs to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Fostemsavir is not a cure for HIV or AIDS.

Fostemsavir is given after several other HIV medications did not work or have stopped working.

Fostemsavir may also be used for purposes not listed in this medication guide.

Fostemsavir side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Fostemsavir may cause serious side effects. Call your doctor at once if you have:

fast or pounding heartbeats, fluttering in your chest;

shortness of breath; and

sudden dizziness (like you might pass out).

Fostemsavir affects your immune system, which may cause certain side effects (even weeks or months after you've taken fostemsavir). Tell your doctor if you have:

signs of a new infection--fever, night sweats, swollen glands, cold sores, cough, wheezing, diarrhea, weight loss;

trouble speaking or swallowing, problems with balance or eye movement, weakness or prickly feeling; or

swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence.

Nausea is the most common side effect of fostemsavir.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Fostemsavir

You should not use fostemsavir if you are allergic to it.

Many drugs can interact and cause dangerous effects. Some drugs should not be used together with fostemsavir. Your doctor may change your treatment plan if you also use:

Carbamazepine;

enzalutamide;

mitotane;

phenytoin;

rifampin; or

St. John's wort.

Tell your doctor if you have ever had liver problems, especially hepatitis B or C.

Tell your doctor if you are pregnant, and use your medications properly to control your infection. HIV can be passed to your baby if the virus is not controlled during pregnancy. Your name may be listed on a registry to track any effects of antiviral medicine on the baby.

Women with HIV or AIDS should not breastfeed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

Fostemsavir is not approved for use by anyone younger than 18 years old.

Relate drugs

How to use Fostemsavir

Usual Adult Dose for HIV Infection:

600 mg orally twice a dayUse: In combination with other antiretroviral agent(s), for the treatment of HIV-1 infection in heavily treatment-experienced patients with multidrug-resistant HIV-1 infection failing their current antiretroviral regimen due to resistance, intolerance, or safety considerations

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What other drugs will affect Fostemsavir

Fostemsavir can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.

Tell your doctor if you take birth control pills or hormone replacement therapy that contains ethinyl estradiol. Fostemsavir can increase your blood levels of ethinyl estradiol, which may increase side effects of this medicine.

When you start or stop taking fostemsavir, your doctor may need to adjust the doses of any "statin" cholesterol medicine you take on a regular basis. This includes atorvastatin, lovastatin, pravastatin, rosuvastatin, simvastatin, Crestor, Vytorin, Zocor, and others.

Other drugs may affect fostemsavir, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.