Ganirelix

Generic name: Ganirelix
Dosage form: subcutaneous solution (250 mcg/0.5 mL)
Drug class: Gonadotropin-releasing hormone antagonists

Usage of Ganirelix

Ganirelix reduces certain hormones in the body, including estrogen.

Ganirelix is used with other medicines to treat infertility in women.

Ganirelix may also be used for purposes not listed in this medication guide.

Ganirelix side effects

Get emergency medical help if you have signs of an allergic Reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some women using ganirelix develop ovarian hyperstimulation syndrome (OHSS), a potentially life-threatening condition. Call your doctor right away if you have symptoms of OHSS:

  • stomach pain, bloating, nausea, vomiting, diarrhea;
  • rapid weight gain, especially in your face and midsection;
  • little or no urination; or
  • pain when you breathe, rapid heart rate, feeling short of breath (especially when lying down).

    • Common side effects of ganirelix may include:

  • stomach pain;
  • headache;
  • vaginal bleeding; or
  • OHSS.

    • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Ganirelix

    You should not use ganirelix if you are allergic to ganirelix or similar medications such as Leuprolide, goserelin, or nafarelin.

    Tell your doctor if you are allergic to latex rubber, or if you have a severe or active allergy.

    May cause birth defects. Do not use if you are pregnant. You may need to have a negative pregnancy test before starting this treatment. Tell your doctor if you become pregnant.

    You should not breastfeed while using ganirelix.

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    How to use Ganirelix

    Usual Adult Dose for Gonadotropin Inhibition:

    During the mid to late portion of the follicular phase: -Administer 250 mcg suBCUTAneously once a day until the day of Human Chorionic Gonadotropin (hCG) administration Comments:-Follicle stimulating hormone (FSH) therapy should be initiated on day 2 or 3 of the cycle.-With the assist of ultrasound, hCG should be administered when a sufficient number of follicles of adequate size are present; final maturation of follicles is induced by administering hCG. Use: For the inhibition of premature luteinizing hormone surges in women undergoing controlled ovarian hyperstimulation.

    Warnings

    Tell your doctor if you have a severe or active allergy.

    What other drugs will affect Ganirelix

    Other drugs may affect ganirelix, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

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