Griseofulvin

Generic name: Griseofulvin
Drug class: Miscellaneous antifungals

Usage of Griseofulvin

Griseofulvin is an antifungal medicine that is used to treat infections such as ringworm, athlete's foot, jock itch, and fungal infections of the scalp, fingernails, or toenails.

Griseofulvin may also be used for purposes not listed in this medication guide.

Griseofulvin side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Griseofulvin may cause serious side effects. Call your doctor at once if you have:

numbness, tingling, or burning pain in your hands or feet;

confusion, trouble with daily activities;

fever, chills, flu symptoms, white patches or sores inside your mouth or throat;

liver problems--loss of appetite, stomach pain (upper right side), dark urine, jaundice (yellowing of the skin or eyes);

kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath, foamy urine;

lupus-like symptoms--muscle or joint pain, flu symptoms, chest pain, and a rash or patchy skin color that worsens in sunlight; or

signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

Common side effects of griseofulvin may include:

nausea, vomiting, upset stomach, diarrhea;

headache, tiredness;

rash;

sleep problems (insomnia); or

dizziness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Griseofulvin

You should not use griseofulvin if you are allergic to it, or if you have:

liver failure;

porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system); or

if you are pregnant or may become pregnant.

Tell your doctor if you have ever had:

liver disease;

lupus; or

an allergy to penicillin.

Taking griseofulvin during the first 3 months of pregnancy may cause birth defects. Do not take griseofulvin if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine.

Griseofulvin can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control (condom, diaphragm, cervical cap, or contraceptive sponge) to prevent pregnancy.

You should not breastfeed while using griseofulvin.

Griseofulvin is not approved for use by anyone younger than 2 years old.

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How to use Griseofulvin

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose as your infection improves. Use the medicine exactly as directed.

Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Tell your doctor if you cannot swallow a tablet whole. You may be able to crush the tablet and sprinkle the medicine into a spoonful of applesauce. Swallow the mixture right away without chewing. Do not save it for later use.

While treating a fungal skin or nail infection, keep the skin areas as clean and dry as possible.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication.

Griseofulvin will not treat a bacterial or viral infection such as the flu or a common cold. Griseofulvin also will not treat certain types of fungal infections, including yeast infections.

It may take up several weeks before your symptoms improve. Nail infections can take several months to clear completely.

Call your doctor if your symptoms do not improve, or if they get worse.

If you use this medicine long-term, you may need frequent medical tests.

Store at room temperature away from moisture, heat, and light.

Warnings

You should not use griseofulvin if you have porphyria or liver failure.

Taking griseofulvin during the first 3 months of pregnancy may harm the unborn baby.

What other drugs will affect Griseofulvin

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Other drugs may affect griseofulvin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

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