Guaifenesin and phenylephrine

Generic name: Guaifenesin And Phenylephrine
Drug class: Upper respiratory combinations

Usage of Guaifenesin and phenylephrine

Guaifenesin and phenylephrine is a combination medicine used in adults and children to treat allergy symptoms such as runny or stuffy nose, sneezing, watery eyes, itching of nose and throat, cough with mucus, sinus pain, and to reduce chest congestion caused by the common cold, hay fever, or other allergies.

There are many brands and forms of guaifenesin and phenylephrine available and not all brands are listed on this leaflet.

Guaifenesin and phenylephrine may also be used for purposes not listed in this medication guide.

Guaifenesin and phenylephrine side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Guaifenesin and phenylephrine may cause serious side effects. Stop using guaifenesin and phenylephrine and call your doctor at once if you have:

  • nervousness, dizziness, sleep problems (insomnia).
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Guaifenesin and phenylephrine

    Do not use guaifenesin and phenylephrine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine. Wait at least 14 days after stopping an MAO inhibitor before you take guaifenesin and phenylephrine.

    Tell your doctor if you have or have ever had:

  • high blood pressure;
  • heart disease;
  • diabetes;
  • a thyroid disorder;
  • urination problems due to an enlarged prostate; or
  • cough with mucus or chronic cough cause by smoking, asthma, chronic obstructive pulmonary disease (COPD) or other breathing disorder.
  • Ask your doctor before using this medicine if you are pregnant or breastfeeding.

    Do not give this medicine to a child without medical advice.

    Relate drugs

    How to use Guaifenesin and phenylephrine

    Usual Adult Dose for Cough and Nasal Congestion:

    Dose referred to by strength of guaiFENesin/phenylephrine (in mg) per unit of measurement:Oral liquids:100/5 per 5 mL:10 mL every 4 hours, maximum 6 doses per dayOral tablets:385/10 per tablet: 1 tablet every 4 hours, maximum 6 doses per day388/10 per tablet: 1 tablet every 4 hours, maximum 6 doses per day395/10 per tablet: 1 tablet every 4 hours, maximum 6 doses per day

    Usual Pediatric Dose for Cough and Nasal Congestion:

    Dose referred to by strength of guaiFENesin/phenylephrine (in mg) per unit of measurement:Oral liquids:50/2.5 per 1 mL:2 to under 6 years: 1 mL every 4 hours, maximum 6 doses per day100/5 per 5 mL:12 years and older: 10 mL every 4 hours, maximum 6 doses per day6 to under 12 years: 5 mL every 4 hours, maximum 6 doses per dayOral tablets:385/10 per tablet:12 years and older: 1 tablet every 4 hours, maximum 6 doses per day6 to under 12 years: 1/2 tablet every 4 hours, maximum 6 doses per day388/10 per tablet: 12 years and older: 1 tablet every 4 hours, maximum 6 doses per day6 to under 12 years: 1/2 tablet every 4 hours, maximum 6 doses per day395/10 per tablet:12 years and older: 1 tablet every 4 hours, maximum 6 doses per day6 to under 12 years: 1/2 tablet every 4 hours, maximum 6 doses per day

    Warnings

    Do not use guaifenesin and phenylephrine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

    Taking more than your recommended dose will not make guaifenesin and phenylephrine more effective, and may cause serious side effects.

    What other drugs will affect Guaifenesin and phenylephrine

    Ask a doctor or pharmacist before using any other medicines that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). Tell your doctor about all other medicines you use. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

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