Guaifenesin and pseudoephedrine

Generic name: Guaifenesin And Pseudoephedrine
Drug class: Upper respiratory combinations

Usage of Guaifenesin and pseudoephedrine

Guaifenesin and pseudoephedrine is a combination medicine used in adults and children to treat allergy symptoms such as runny or stuffy nose, sneezing, watery eyes, itching of nose and throat, cough with mucus, sinus pain, and to reduce chest congestion caused by the common cold, hay fever, or other allergies.

There are many brand forms of guaifenesin and pseudoephedrine available, and not all brands are listed on this leaflet.

Guaifenesin and pseudoephedrine may also be used for purposes not listed in this medication guide.

Guaifenesin and pseudoephedrine side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Guaifenesin and pseudoephedrine may cause serious side effects. Stop using guaifenesin and pseudoephedrine and call your doctor at once if you have:

  • nervousness, dizziness, sleep problems (insomnia).
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Guaifenesin and pseudoephedrine

    Do not use guaifenesin and pseudoephedrine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

    Tell your doctor if you have or have ever had:

  • heart disease;
  • high blood pressure;
  • diabetes;
  • a thyroid disorder;
  • urination problems due to an enlarged prostate; or
  • cough with mucus or chronic cough cause by smoking, asthma, chronic obstructive pulmonary disease (COPD) or other breathing disorder.
  • Tell your doctor if you are pregnant or breastfeeding.

    Do not give this medicine to a child without medical advice.

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    How to use Guaifenesin and pseudoephedrine

    Usual Adult Dose for Cough and Nasal Congestion:

    Immediate release tablets: 1 tablet orally every 4 hoursMaximum dose: 4 tablets per 24 hoursExtended release (600 mg/ 60 mg) tablets: 2 tablets orally every 12 hoursMaximum dose: 4 tablets per 24 hoursMaximum strength (1200 mg/ 120 mg) extended release tablets: 1 tablet orally every 12 hoursMaximum dose: 2 tablets per 24 hours

    Usual Pediatric Dose for Cough and Nasal Congestion:

    Immediate release tablets:12 years and older: 1 tablet orally every 4 hoursMaximum dose: 4 tablets per 24 hours6 to 12 years: One half tablet orally every 4 hoursMaximum dose: 2 tablets per 24 hoursExtended release (600 mg/ 60 mg) tablets: 12 years and older: 2 tablets orally every 12 hoursMaximum dose: 4 tablets per 24 hoursMaximum strength (1200 mg/ 120 mg) extended release tablets:12 years and older: 1 tablet orally every 12 hoursMaximum dose: 2 tablets per 24 hours25 mg/ 7.5 mg/ mL liquid: 2 to under 6 years (11 to 21 kg): 2 mL every 4 to 6 hoursMaximum dose: 4 doses per 24 hours

    Warnings

    Do not use guaifenesin and pseudoephedrine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

    Taking more than your recommended dose will not make guaifenesin and pseudoephedrine more effective, and may cause serious side effects.

    What other drugs will affect Guaifenesin and pseudoephedrine

    Ask a doctor or pharmacist before using any other medicines that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). Tell your doctor about all other medicines you use. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

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