Guaifenesin, hydrocodone, and pseudoephedrine

Generic name: Guaifenesin, Hydrocodone, And Pseudoephedrine
Dosage form: oral liquid (200 mg-2.5 mg-30 mg/5 mL)
Drug class: Upper respiratory combinations

Usage of Guaifenesin, hydrocodone, and pseudoephedrine

Guaifenesin, hydrocodone, and pseudoephedrine is a combination medicine used to treat cough, stuffy nose, sinus congestion, and chest congestion caused by the common cold.

guaifenesin, hydrocodone, and pseudoephedrine will not treat a cough with mucus, or cough that is caused by smoking, emphysema, or chronic bronchitis.

Guaifenesin, hydrocodone, and pseudoephedrine contains a narcotic cough medicine and may be habit-forming.

Guaifenesin, hydrocodone, and pseudoephedrine may also be used for other purposes not listed in this medication guide.

Guaifenesin, hydrocodone, and pseudoephedrine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

This medicine can slow or stop your breathing, and death may occur. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

This medicine may cause serious side effects. Stop using this medicine and call your doctor at once if you have:

  • noisy breathing, sighing, shallow breathing;
  • confusion, severe weakness or drowsiness;
  • tremors, severe restlessness;
  • a seizure;
  • irregular heartbeats;
  • severe headache, blurred vision, pounding in your neck or ears;
  • a light-headed feeling, like you might pass out;
  • severe constipation, stomach pain; or
  • adrenal gland problems--nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.
  • Serious side effects may be more likely in older adults and those who are overweight, malnourished, or debilitated.

    Common side effects of guaifenesin, hydrocodone, and pseudoephedrine may include:

  • dizziness, drowsiness;
  • headache;
  • sleep problems (insomnia);
  • nausea; or
  • low blood pressure.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Guaifenesin, hydrocodone, and pseudoephedrine

    Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

    You should not use this medicine if you are allergic to guaifenesin, hydrocodone, or pseudoephedrine, or if you have:

  • narrow-angle glaucoma;
  • severe or uncontrolled high blood pressure;
  • coronary artery disease (clogged arteries); or
  • if you are unable to urinate.
  • This medicine is not approved for use by anyone younger than 18 years old.

    Tell your doctor if you have ever had:

  • asthma or other breathing problems;
  • a head injury or increased pressure inside your skull;
  • diabetes;
  • thyroid disorder;
  • Addison's disease (an adrenal gland disorder);
  • liver or kidney disease;
  • an enlarged prostate or urination problems; or
  • stomach problems.
  • If you use hydrocodone while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

    Do not breast-feed. Hydrocodone can pass into breast milk and may cause drowsiness, breathing problems, or death in a nursing baby.

    Relate drugs

    How to use Guaifenesin, hydrocodone, and pseudoephedrine

    Usual Adult Dose for Cough and Nasal Congestion:

    10 mL orally every 4 to 6 hoursMaximum dose: 40 mL in 24 hours Comments:-Each 5 mL contains hydrocodone 2.5 mg; pseudoephedrine 30 mg; guaifenesin 200 mg -Measure dose with accurate measuring device. Use: Symptomatic relief of cough, nasal congestion, and to loosen mucus associated with the common cold.

    Warnings

    MISUSE OF OPIOID MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it.

    Fatal side effects can occur if you use guaifenesin, hydrocodone, and pseudoephedrine with alcohol, or with other drugs that cause drowsiness or slow your breathing.

    What other drugs will affect Guaifenesin, hydrocodone, and pseudoephedrine

    Using this medicine with other drugs that slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

    Opioid medication can interact with many other drugs and cause dangerous side effects or death. Be sure your doctor knows if you also use:

  • cold or allergy medicines, bronchodilator asthma/COPD medication, or a diuretic ("water pill");
  • medicines for motion sickness, irritable bowel syndrome, or overactive bladder;
  • other narcotic medications--opioid pain medicine or prescription cough medicine;
  • a sedative like Valium--Diazepam, alprazolam, lorazepam, Xanax, Klonopin, Versed, and others; or
  • drugs that make you sleepy or slow your breathing--a sleeping pill, muscle relaxer, medicine to treat mood disorders or mental illness.
  • This list is not complete. Other drugs may affect guaifenesin, hydrocodone, and pseudoephedrine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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