Hyaluronan

Generic name: Hyaluronan
Drug class: Viscosupplementation agents

Usage of Hyaluronan

Hyaluronan is similar to the fluid that surrounds the joints in your body. This fluid acts as a lubricant and shock absorber for the joints.

Hyaluronan is used to treat knee pain caused by osteoarthritis.

Hyaluronan is usually given after other arthritis medications have been tried without success.

Hyaluronan may also be used for purposes not listed in this medication guide.

Hyaluronan side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Hyaluronan may cause serious side effects. Call your doctor at once if you have:

bleeding;

increased knee pain; or

signs of infection (warmth, swelling, redness) around your knee.

Common side effects of hyaluronan may include:

joint pain, stiffness, or swelling;

itching, numbness, or tingling;

headache, dizziness;

back pain;

swelling, pain, redness, or mild discomfort where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Hyaluronan

You should not be treated with hyaluronan if you are allergic to it, or if you have:

an allergy to gram positive bacteria proteins (ask your doctor if you are not sure);

a bleeding or blood clotting disorder such as hemophilia; or

an infection in your knee or in the skin around your knee.

It is not known whether hyaluronan will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using hyaluronan.

It is not known whether hyaluronan passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Hyaluronan is not approved for use by anyone younger than 21 years old.

Relate drugs

How to use Hyaluronan

Usual Adult Dose for Osteoarthritis:

Inject the contents of one prefilled syringe intraarticularly into the knee once a week for 3 to 4 weeksUse: For the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy and to simple analgesics (e.g., acetaminophen)

Warnings

You should not receive hyaluronan if you have a bleeding disorder, certain allergies, or an infection in your knee or in the skin around your knee.

What other drugs will affect Hyaluronan

Other drugs may interact with hyaluronan, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Disclaimer

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