Hydrochlorothiazide
Generic name: Hydrochlorothiazide
Drug class:
Thiazide diuretics
Usage of Hydrochlorothiazide
Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.
Hydrochlorothiazide is used to treat high blood pressure (hypertension).
Hydrochlorothiazide is also used to treat fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or kidney disorders, or edema caused by taking steroids or estrogen.
Hydrochlorothiazide side effects
Get emergency medical help if you have signs of an allergic reaction to hydrochlorothiazide (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Call your doctor at once if you have:
Common hydrochlorothiazide side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Hydrochlorothiazide
You should not use hydrochlorothiazide if you are allergic to it, or if you are unable to urinate.
To make sure hydrochlorothiazide is safe for you, tell your doctor if you have ever had:
Tell your doctor if you are pregnant or plan to become pregnant. If you take hydrochlorothiazide during pregnancy, your newborn baby may develop jaundice or other problems.
You should not breastfeed while using this medicine.
Hydrochlorothiazide is not approved for use by anyone younger than 18 years old.
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How to use Hydrochlorothiazide
Usual Adult Dose for Edema:
Usual dose: 25 mg to 100 mg orally once or twice daily Comments: -Some patients respond to intermittent therapy, (i.e., administration on alternate days or on 3 to 5 days each week). Excessive response and undesirable electrolyte imbalance are less likely to occur with intermittent dosing.
Usual Adult Dose for Hypertension:
Initial dose: 25 mg orally once daily Maintenance dose: May increase to 50 mg orally daily, as a single or 2 divided doses Comments: -Patients usually do not require doses in excess of 50 mg daily when used concomitantly with other antihypertensive agents.
Usual Adult Dose for Nephrocalcinosis:
Initial: 25 mg orally once daily Maintenance dose: May increase to 50 mg twice daily
Usual Adult Dose for Osteoporosis:
Initial: 25 mg orally once daily Maintenance dose: May increase to 50 mg daily
Usual Adult Dose for Diabetes Insipidus:
Initial: 50 mg orally once daily Maintenance dose: May increase to 100 mg orally daily
Usual Pediatric Dose for Edema:
Less than 6 months: Up to 3 mg/kg/day (up to 1.5 mg/pound) orally in 2 divided doses Less than 2 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses Maximum dose 37.5 mg per day 2 to 12 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses Maximum dose 100 mg per day
Usual Pediatric Dose for Hypertension:
Less than 6 months: Up to 3 mg/kg/day (up to 1.5 mg/pound) orally in 2 divided doses Less than 2 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses Maximum dose 37.5 mg per day 2 to 12 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses Maximum dose 100 mg per day
Warnings
You should not use hydrochlorothiazide if you are unable to urinate.
Before using hydrochlorothiazide, tell your doctor if you have liver disease, kidney disease, glaucoma, asthma or allergies, gout, diabetes, or if you are allergic to sulfa drugs or penicillin.
Avoid drinking alcohol, which can increase some of the side effects of hydrochlorothiazide .
Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.
There are many other drugs that can interact with hydrochlorothiazide. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
If you are being treated for high blood pressure, keep using hydrochlorothiazide even if you feel fine. High blood pressure often has no symptoms.
What other drugs will affect Hydrochlorothiazide
Taking hydrochlorothiazide with other drugs that make you light-headed can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Tell your doctor about all your other medicines, especially:
This list is not complete. Other drugs may affect hydrochlorothiazide, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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