Hydrochlorothiazide and bisoprolol

Generic name: Hydrochlorothiazide And Bisoprolol
Brand names: Ziac
Dosage form: oral tablet (10 mg-6.25 mg; 2.5 mg-6.25 mg; 5 mg-6.25 mg)
Drug class: Beta blockers with thiazides

Usage of Hydrochlorothiazide and bisoprolol

Hydrochlorothiazide is a thiazide diuretic (water pill). Bisoprolol is a beta-blocker.

Hydrochlorothiazide and bisoprolol is a combination medicine used to treat high blood pressure (hypertension).

Hydrochlorothiazide and bisoprolol may also be used for purposes not listed in this medication guide.

Hydrochlorothiazide and bisoprolol side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Hydrochlorothiazide and bisoprolol may cause serious side effects. Call your doctor at once if you have:

chest pain;

fast, slow, or uneven heartbeats;

a light-headed feeling, like you might pass out;

blurred vision, tunnel vision, eye pain, or seeing halos around lights;

shortness of breath (even with mild exertion), swelling, rapid weight gain;

liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

signs of an electrolyte imbalance--increased thirst or urination, constipation, muscle pain or weakness, leg cramps, numbness or tingling, feeling jittery, irregular heartbeats, fluttering in your chest, or a choking feeling;

low blood sugar--headache, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky.

Common side effects of hydrochlorothiazide and bisoprolol may include:

dizziness;

feeling weak or tired;

diarrhea, nausea, indigestion;

headache; or

cough.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Hydrochlorothiazide and bisoprolol

You should not use this medicine if you are allergic to hydrochlorothiazide or bisoprolol, or if you have:

severe or uncontrolled heart failure;

slow heartbeats that have caused you to faint;

a serious heart condition called "sick sinus syndrome" or "AV block" (2nd or 3rd degree);

an allergy to sulfa drugs; or

if you are unable to urinate.

Tell your doctor if you have ever had:

congestive heart failure;

asthma or other breathing disorder;

diabetes;

a thyroid disorder;

glaucoma;

peripheral vascular disease such as Raynaud's syndrome;

kidney disease;

liver disease (or cirrhosis);

lupus;

gout; or

an allergy to sulfa drugs or penicillin.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breastfeed while using this medicine.

This medicine is not approved for use by anyone younger than 18 years old.

Relate drugs

How to use Hydrochlorothiazide and bisoprolol

Usual Adult Dose for Hypertension:

Initial dose: Bisoprolol 2.5 mg-Hydrochlorothiazide 6.25 mg orally once a dayMaximum dose: Bisoprolol 20 mg-Hydrochlorothiazide 12.5 mg orally once a dayComments:-Increase the dose every 14 days if optimal response not achieved.-This drug may be substituted for titrated individual components (e.g., inadequate control on bisoprolol 2.5 to 20 mg or adequate control on hydrochlorothiazide 50 mg but with significant potassium loss). -Abrupt discontinuation should be avoided; taper therapy gradually over approximately 2 weeks.-If withdrawal symptoms occur, therapy may be temporarily reinstituted.

Warnings

You should not use hydrochlorothiazide and bisoprolol if you are unable to urinate. You should not use hydrochlorothiazide and bisoprolol if you have a serious heart condition such as "sick sinus syndrome" or "AV block," severe heart failure, or slow heartbeats that have caused you to faint.

What other drugs will affect Hydrochlorothiazide and bisoprolol

Tell your doctor about all your other medicines, especially:

colestipol or cholestyramine;

insulin or oral diabetes medicine;

lithium;

sedatives or narcotic medicine;

heart or blood pressure medicine--clonidine, digoxin, diltiazem, disopyramide, reserpine, verapamil, and others;

NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), Celecoxib, diclofenac, indomethacin, meloxicam, and others; or

steroid medicine--prednisone and others.

This list is not complete. Other drugs may affect hydrochlorothiazide and bisoprolol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.