Hydrochlorothiazide and candesartan

Generic name: Hydrochlorothiazide And Candesartan
Brand names: Atacand HCT
Dosage form: oral tablet (16 mg-12.5 mg; 32 mg-12.5 mg; 32 mg-25 mg)
Drug class: Angiotensin II inhibitors with thiazides

Usage of Hydrochlorothiazide and candesartan

Hydrochlorothiazide and Candesartan is a combination medicine used to treat high blood pressure (hypertension).

Hydrochlorothiazide and candesartan may also be used for purposes not listed in this medication guide.

Hydrochlorothiazide and candesartan side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

In rare cases, hydrochlorothiazide and candesartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.

Also call your doctor at once if you have:

eye pain, vision problems;

a light-headed feeling, like you might pass out;

little or no urinating;

jaundice (yellowing of the skin or eyes);

easy bruising, unusual bleeding; or

signs of an electrolyte imbalance--increased thirst or urination, confusion, vomiting, constipation, muscle pain or weakness, leg cramps, bone pain, lack of energy, irregular heartbeats, tingly feeling.

Common side effects of hydrochlorothiazide and candesartan may include:

dizziness;

back pain; or

cold or flu symptoms.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Hydrochlorothiazide and candesartan

You should not use this medicine if you are allergic to candesartan or hydrochlorothiazide, or if:

you are unable to urinate; or

you are allergic to sulfa drugs.

If you have diabetes, do not use hydrochlorothiazide and candesartan together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking hydrochlorothiazide and candesartan with aliskiren if you have kidney disease.

Tell your doctor if you have ever had:

liver disease;

congestive heart failure;

glaucoma;

low or high levels of potassium in your blood;

asthma or allergies;

high cholesterol or triglyceride levels;

gout;

lupus;

diabetes; or

an allergy to penicillin.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. This medicine can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

You should not breastfeed while using this medicine.

Relate drugs

How to use Hydrochlorothiazide and candesartan

Usual Adult Dose for Hypertension:

Candesartan 16 to 32 mg-Hydrochlorothiazide 12.5 to 50 mg orally daily in 1 to 2 divided dosesComments:-The recommended starting dose of candesartan is 16 mg orally once a day when used as monotherapy in patients who are not volume depleted; doses larger than 32 mg do not appear to have a greater blood pressure lowering effect.-A patient whose blood pressure remains uncontrolled on candesartan 32 mg can expect an incremental effect from candesartan 32 mg-hydrochlorothiazide 12.5 mg-A patient whose blood pressure remains uncontrolled on hydrochlorothiazide 25 mg can expect an incremental effect from candesartan 16 mg-hydrochlorothiazide 12.5 mg; a patient whose blood pressure is controlled on hydrochlorothiazide 25 mg but is experiencing decreases in serum potassium can expect the same or incremental blood pressure effects from candesartan 16 mg-hydrochlorothiazide 12.5 mg and serum potassium may improve.-Maximal antihypertensive effect can be expected within 4 weeks of treatment initiation.

Warnings

Do not use if you are pregnant. If you become pregnant, stop taking hydrochlorothiazide and candesartan and tell your doctor right away.

If you have diabetes, do not use hydrochlorothiazide and candesartan together with any medication that contains aliskiren (a blood pressure medicine).

What other drugs will affect Hydrochlorothiazide and candesartan

Tell your doctor about all your other medicines, especially:

lithium; or

NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), Celecoxib, diclofenac, indomethacin, meloxicam, and others.

This list is not complete. Other drugs may affect hydrochlorothiazide and candesartan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

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