Hydrochlorothiazide and captopril

Generic name: Hydrochlorothiazide And Captopril
Dosage form: oral tablet (25 mg-15 mg; 25 mg-25 mg; 50 mg-15 mg; 50 mg-25 mg)
Drug class: ACE inhibitors with thiazides

Usage of Hydrochlorothiazide and captopril

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Captopril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme. Captopril lowers blood pressure and also relieves symptoms of fluid retention.

Hydrochlorothiazide and captopril is a combination medicine used to treat hypertension (high blood pressure).

Hydrochlorothiazide and captopril may also be used for purposes not listed in this medication guide.

Hydrochlorothiazide and captopril side effects

Get emergency medical help if you have signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.

Hydrochlorothiazide and captopril may cause serious side effects. Call your doctor at once if you have:

a light-headed feeling, like you might pass out;

eye pain, vision problems;

little or no urinating;

chest pain, pounding heartbeats or fluttering in your chest;

swelling, weight gain, shortness of breath;

pale skin, easy bruising or bleeding;

sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, trouble swallowing;

high potassium--nausea, slow or unusual heart rate, weakness, loss of movement;

low potassium--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling;

low levels of sodium--headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady; or

severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common side effects of hydrochlorothiazide and captopril may include:

cough;

mild itching or rash;

joint pain;

numbness in your hands or feet;

decreased sense of taste; or

flushing (warmth, redness, or tingly feeling).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Hydrochlorothiazide and captopril

You should not use this medication if you are allergic to hydrochlorothiazide or captopril, or if:

you are unable to urinate;

you are allergic to sulfa drugs; or

you are allergic to any other ACE inhibitor, such as Benazepril, enalapril, fosinopril, lisinopril, quinapril, ramipril, trandolapril, and others.

If you have diabetes, do not use hydrochlorothiazide and captopril together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo).

You may also need to avoid taking hydrochlorothiazide and captopril with aliskiren if you have kidney disease.

To make sure hydrochlorothiazide and captopril is safe for you, tell your doctor if you have:

kidney disease (or if you are on dialysis);

cirrhosis or other liver disease;

glaucoma;

congestive heart failure;

gout;

lupus;

diabetes; or

an allergy to sulfa drugs or penicillin.

Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. Captopril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

Hydrochlorothiazide and captopril can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.

Relate drugs

How to use Hydrochlorothiazide and captopril

Usual Adult Dose for Hypertension:

Initial dose: Captopril 25 mg-Hydrochlorothiazide 15 mg orally once a day 1 hour before mealsMaximum dose: Captopril 150 mg-Hydrochlorothiazide 50 mg per dayComments: The full effect of a given dose may not be attained for 6 to 8 weeks; dose adjustments should be made at 6 week intervals, unless the clinical situation demands more rapid adjustment.Use: Treatment of hypertension as initial therapy or substituted for previously titrated doses of the individual components.

Warnings

Do not use if you are pregnant. If you become pregnant, stop taking hydrochlorothiazide and captopril and tell your doctor right away.

You should not use this medicine if you are unable to urinate, or if you are allergic to sulfa drugs or any ACE inhibitor.

If you have diabetes, do not use hydrochlorothiazide and captopril together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo).

What other drugs will affect Hydrochlorothiazide and captopril

Tell your doctor about all your current medicines and any you start or stop using, especially:

lithium; or

other diuretics (water pills) or blood pressure medications.

This list is not complete. Other drugs may interact with hydrochlorothiazide and captopril, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Disclaimer

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