Isovue-M-300

Generic name: Iopamidol
Drug class: Non-ionic iodinated contrast media

Usage of Isovue-M-300

Isovue-M-300 is a radiopaque (RAY dee oh payk) contrast agent. This medicine contains iodine, a substance that absorbs x-rays. Radiopaque contrast agents are used to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on a CT scan or other radiologic (x-ray) examination.

Isovue-M-300 is used to help diagnose certain disorders of the heart, brain, blood vessels, and nervous system.

Isovue-M-300 may also be used for purposes not listed in this medication guide.

Isovue-M-300 side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.

Isovue-M-300 may cause serious side effects. Call your doctor at once if you have:

a light-headed feeling, like you might pass out;

swelling, rapid weight gain, little or no urinating;

wheezing or trouble breathing;

seizure (convulsions);

swelling in your neck or throat (enlarged thyroid);

thyroid symptoms--extreme tired feeling, dry skin, joint pain or stiffness, muscle pain or weakness, hoarse voice, feeling more sensitive to cold temperatures, weight gain;

heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;

signs of a blood clot in the lung--chest pain, sudden cough or shortness of breath, coughing up blood; or

signs of a stroke--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance.

Common side effects of Isovue-M-300 may include:

chest pain;

slow heart rate;

hot flashes, burning sensation;

flushing (warmth, redness, or tingly feeling);

nausea;

hives; or

dizziness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Isovue-M-300

Tell your doctor if you have ever had:

any type of reaction to another contrast agent;

liver or kidney disease;

heart disease, including congestive heart failure;

a stroke, blood clots, or coronary artery disease;

asthma, hay fever, food allergies;

epilepsy or other seizure disorder;

sickle cell anemia;

diabetes;

an active infection;

pheochromocytoma (tumor of the adrenal gland);

multiple myeloma (bone cancer); or

a thyroid disorder.

It is not known whether Isovue-M-300 will harm an unborn baby. Tell your doctor if you are pregnant.

Tell your doctor if you are breast-feeding.

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How to use Isovue-M-300

Isovue-M-300 is given as an infusion into a vein or artery. A healthcare provider will give you this injection.

You may be given medication to prevent certain side effects while you are receiving Isovue-M-300.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Isovue-M-300 is injected.

Drink extra fluids before and after your radiologic test. Isovue-M-300 can cause you to get dehydrated, which can lead to dangerous effects on your kidneys. Follow your doctor's instructions about the types and amount of fluids you should drink before and after your test.

Older adults may need special care to avoid becoming dehydrated. Your kidney function may need to be checked after you have received Isovue-M-300.

Some people receiving Isovue-M-300 have had reactions that did not start until 30 to 60 minutes after the medicine was first given. Your caregivers may want to watch you during this period of time after your injection. This is to make sure you do not have any unwanted side effects or delayed reactions.

Isovue-M-300 can interfere with certain medical tests for up to 16 days after you are treated with this medicine. Tell any doctor who treats you that you have recently received this medicine.

Warnings

You should not receive Isovue-M-300 if you have any type of active infection.

What other drugs will affect Isovue-M-300

Tell your doctor about all your current medicines, especially:

diabetes medicine that contains metformin (Glucophage, Glucovance, Actoplus Met, PrandiMet, Avandamet, Kombiglyze, Janumet, Kazano, Invokamet, Jentadueto, Xigduo, Synjardy, Metaglip, and others).

This list is not complete. Other drugs may affect Isovue-M-300, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.