Isradipine

Generic name: Isradipine
Dosage form: oral capsule (2.5 mg; 5 mg)
Drug class: Calcium channel blocking agents

Usage of Isradipine

Isradipine is a calcium channel blocker that is used to treat hypertension (high blood pressure).

Isradipine is sometimes used together with a diuretic or "water pill."

Isradipine may also be used for purposes not listed in this medication guide.

Isradipine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Isradipine may cause serious side effects. Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • pounding heartbeats or fluttering in your chest;
  • flushing (warmth, redness, or tingly feeling);
  • tiredness; or
  • heart problems--swelling, rapid weight gain, feeling short of breath.
  • Common side effects of isradipine may include:

  • flushing;
  • headache, dizziness;
  • swelling;
  • fast heartbeats; or
  • upset stomach.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Isradipine

    You should not use isradipine if you are allergic to it.

    Tell your doctor if you have ever had:

  • congestive heart failure;
  • liver disease; or
  • kidney disease.
  • Older adults may be more sensitive to the effects of isradipine.

    It is not known whether isradipine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

    You should not breast-feed while using isradipine.

    Relate drugs

    How to use Isradipine

    Usual Adult Dose for Hypertension:

    Initial dose:Immediate-release capsules: 2.5 mg orally twice a dayControlled-release tablets: 5 mg orally once a dayMaintenance dose: The dose may be adjusted as needed and tolerated in increments of 5 mg at 2 to 4 week intervals.The maximum recommended daily dose for the immediate-release capsules is 20 mg, although most patients show no additional response to doses above 10 mg/day. The maximum recommended dose for the controlled-release tablets is 20 mg/day.

    Warnings

    Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

    What other drugs will affect Isradipine

    Tell your doctor about all your other medicines, especially:

  • cimetidine (Tagamet);
  • fentanyl; or
  • rifampin.
  • This list is not complete. Other drugs may affect isradipine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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