Kanuma

Generic name: Sebelipase Alfa
Drug class: Lysosomal enzymes

Usage of Kanuma

Kanuma is a copy of an enzyme that is normally produced in the body to help break down fats and keep them from building up in your cells.

Kanuma is used to treat lysosomal acid lipase deficiency. This is a life-threatening genetic disorder that can damage major organs in the body and lead to early death. This medicine replaces the missing enzyme when the body does not have enough of its own.

Kanuma may also be used for purposes not listed in this medication guide.

Kanuma side effects

Get emergency medical help if you have signs of an allergic Reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your caregiver right away if you feel itchy, flushed, chilled or feverish, or if you have a runny nose, eye irritation, diarrhea, chest discomfort, or trouble breathing.

Kanuma may cause serious side effects. Call your doctor at once if you have:

severe skin rash, itching, or swelling;

agitation, irritability;

stomach pain; or

low red blood cells (anemia)--pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating.

Common side effects of Kanuma may include:

fever, weakness;

runny nose, sinus pain, sore throat, cough;

rash;

diarrhea, constipation;

nausea, vomiting; or

headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Kanuma

You should not be treated with Kanuma if you are allergic to it.

To make sure Kanuma is safe for you, tell your doctor if you have:

an allergy to eggs or egg products.

It is not known whether Kanuma will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether Sebelipase alfa passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Kanuma is not approved for use by anyone younger than 1 month old.

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How to use Kanuma

Kanuma is injected into a vein through an IV. A healthcare provider will give you this injection.

Kanuma is usually given once every other week. The IV infusion must be given slowly and can take 1 to 2 hours to complete.

You will be watched closely during and after receiving Kanuma, to make sure you do not have an allergic reaction to the medication.

Tell your doctor if you have any changes in weight. Kanuma doses are based on weight (especially in children), and any changes may affect the dose.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What other drugs will affect Kanuma

Other drugs may interact with sebelipase alfa, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

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