Krintafel

Generic name: Tafenoquine
Drug class: Antimalarial quinolines

Usage of Krintafel

Krintafel is an anti-malaria medicine that interferes with the growth of parasites in the human body. Parasites that cause malaria can enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.

Krintafel is used to prevent malaria caused by the Plasmodium vivax parasite.

Krintafel is for use in adults and children at least 16 years old who are also using another medicine called chloroquine.

Krintafel may also be used for purposes not listed in this medication guide.

Krintafel side effects

Get emergency medical help if you have signs of an allergic reaction: hives; dizziness, difficult breathing; swelling of your face, lips, tongue, or throat.

Krintafel may cause serious side effects. Call your doctor at once if you have:

pale or yellowed skin, dark colored urine;

darkening of your mouth, lips, or fingernails;

fast heartbeats, shortness of breath;

a headache, or light-headed feeling (like you might pass out);

confusion, tiredness; or

new or worsening mental health problems--anxiety, strange dreams, trouble sleeping.

Common side effects of Krintafel may include:

nausea, vomiting;

abnormal hemoglobin tests;

dizziness; or

headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Krintafel

You should not use Krintafel if:

you have a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency; or

you are allergic to Krintafel or similar medicines (such as primaquine).

Do not breastfeed while using Krintafel if your baby has G6PD deficiency (or has not been tested for it). If the baby does have G6PD deficiency, you should also not breastfeed for at least 3 months after your last dose of tafenoquine.

Krintafel may harm an unborn baby. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control to prevent pregnancy while taking this medicine, and for at least 3 months after your last dose.

Tell your doctor right away if you become pregnant.

Tell your doctor if you have ever had:

a mental illness; or

liver or kidney disease.

Krintafel is not approved for use by anyone younger than 16 years old.

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How to use Krintafel

Before you take Krintafel, your doctor will perform a test to make sure you do not have G6PD deficiency.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

The usual dose of tafenoquine is 2 tablets taken at one time. Start taking Krintafel on the first or second day you start taking chloroquine.

Take with food.

Swallow the tablets whole and do not crush, chew, or break them.

If you vomit within 1 hour after taking Krintafel, you may need to take a second dose. Call your doctor for instructions.

Call your doctor as soon as possible if you have been exposed to malaria, or if you have fever, vomiting, or diarrhea during or after a stay in an area where malaria is common.

Use protective clothing, insect repellents, and mosquito netting around your bed to further prevent mosquito bites that could cause malaria.

No medication is 100% effective in treating or preventing all types of malaria. For best results, keep using the medication as directed.

Store at room temperature away from moisture and heat.

Keep the tablets in their original container, along with the packet or canister of moisture-absorbing preservative.

Warnings

You should not use Krintafel if you have a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency. Your doctor will perform a test to make sure you do not have this condition.

What other drugs will affect Krintafel

Other drugs may affect Krintafel, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

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