Lamivudine and tenofovir

Generic name: Lamivudine And Tenofovir
Dosage form: oral tablet (300 mg-300 mg)
Drug class: Antiviral combinations

Usage of Lamivudine and tenofovir

Lamivudine and Tenofovir are antiviral medicines that prevent human immunodeficiency virus (HIV) from multiplying in your body.

Lamivudine and tenofovir is a combination medicine used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Lamivudine and tenofovir is not a cure for HIV or AIDS.

lamivudine and tenofovir is used in adults and children who weigh at least 77 pounds.

Lamivudine and tenofovir may also be used for purposes not listed in this medication guide.

Lamivudine and tenofovir side effects

Get emergency medical help if you have signs of an allergic Reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Lamivudine and tenofovir may cause serious side effects. Call your doctor at once if you have:

new or worsening bone pain;

muscle weakness;

pain in your arms, hands, legs, or feet;

swelling around your midsection;

kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or

signs of liver or pancreas problems--loss of appetite, upper stomach pain (that may spread to your back), nausea or vomiting, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Lamivudine and tenofovir affects your immune system, which may cause certain side effects (even weeks or months after you've taken this medicine). Tell your doctor if you have:

signs of a new infection--fever, night sweats, swollen glands, cold sores, cough, wheezing, diarrhea, weight loss;

trouble speaking or swallowing, problems with balance or eye movement, weakness or prickly feeling; or

swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence.

Common side effects of lamivudine and tenofovir may include:

headache;

pain;

diarrhea;

rash;

depression; or

changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Lamivudine and tenofovir

You should not use this medicine if you are allergic to lamivudine or tenofovir.

Tell your doctor if you have ever had:

liver disease, including cirrhosis or hepatitis B or C (especially if you also use ribavirin or interferon alfa);

kidney disease (or if you are on dialysis);

a pancreas disorder; or

bone problems, including osteoporosis or a broken bone.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, if you've taken HIV medication for a long time, or if you are a woman. Ask your doctor about your risk.

Tell your doctor if you are pregnant, and use your medications properly to control your infection. HIV can be passed to your baby if the virus is not controlled during pregnancy. Your name may be listed on a registry to track any effects of antiviral medicine on the baby.

Women with HIV or AIDS should not breastfeed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

Relate drugs

How to use Lamivudine and tenofovir

Usual Adult Dose for HIV Infection:

1 tablet orally once a dayUse: In combination with other antiretroviral agents, for the treatment of HIV-1 infection

Usual Pediatric Dose for HIV Infection:

At least 35 kg: 1 tablet orally once a dayUse: In combination with other antiretroviral agents, for the treatment of HIV-1 infection

Warnings

lamivudine and tenofovir can cause serious side effects. Call your doctor at once if you have symptoms such as upper stomach pain, loss of appetite, dark urine, yellowing of your skin or eyes, bone pain, or muscle weakness.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.

If you've ever had hepatitis B, it may become active or get worse after you stop using lamivudine and tenofovir. You may need frequent liver function tests for several months.

What other drugs will affect Lamivudine and tenofovir

Lamivudine and tenofovir can harm your kidneys, especially if you also use certain medicines for infections, cancer, osteoporosis, organ transplant rejection, bowel disorders, high blood pressure, or pain or arthritis (including Advil, Motrin, and Aleve).

Tell your doctor about all your other medicines, especially other antivirals to treat HIV or hepatitis C.

Other drugs may affect lamivudine and tenofovir, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.