Lemborexant

Generic name: Lemborexant
Brand names: Dayvigo
Dosage form: oral tablet (10 mg; 5 mg)
Drug class: Miscellaneous anxiolytics , Antineoplastic Agents

Usage of Lemborexant

Lemborexant is a sleep medicine that is used to treat insomnia (trouble falling asleep or staying asleep).

Lemborexant may also be used for purposes not listed in this medication guide.

Lemborexant side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some people using lemborexant have engaged in activity while not fully awake and later had no memory of it. This may include walking, driving, eating, having sex, or making phone calls. If this happens to you, call your doctor right away.

Lemborexant may cause serious side effects. Call your doctor at once if you have:

  • trouble moving or talking when you first wake up;
  • a weak feeling in your legs;
  • unusual thoughts or behavior;
  • anxiety, agitation, depression;
  • memory problems;
  • confusion, hallucinations; or
  • worsening depression or thoughts about hurting yourself.
  • Older adults have a higher risk of falls due to drowsiness caused by lemborexant.

    Common side effects of lemborexant may include:

  • drowsiness during the day after taking lemborexant.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Lemborexant

    You should not use lemborexant if you have:

  • narcolepsy; or
  • severe liver disease.
  • Tell your doctor if you have ever had:

  • depression, mental illness, or thoughts about suicide;
  • drug or alcohol abuse or addiction;
  • breathing problems, sleep apnea (breathing stops during sleep);
  • liver or kidney disease;
  • sudden muscle weakness;
  • excessive sleepiness during normal waking hours; or
  • if you have ever fallen asleep at unexpected times.
  • Tell your doctor if you are pregnant or breastfeeding.

    If you are pregnant, your name may be listed on a pregnancy registry to track the effects of lemborexant on the baby.

    Lemborexant is not approved for use by anyone younger than 18 years old.

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    How to use Lemborexant

    Usual Adult Dose for Insomnia:

    5 mg orally once a day at bedtime-Maximum dose: 10 mg once at bedtimeUse: For the treatment of patients with insomnia, characterized by difficulties with sleep onset and/or sleep maintenance.

    Warnings

    Take lemborexant right before you get into bed. Never take this medicine if you do not have 7 hours to sleep before being active again.

    Your reactions may be impaired the morning after you take lemborexant. Do not drive or do anything that requires you to be alert. Drowsiness can cause falls, accidents, or severe injuries.

    What other drugs will affect Lemborexant

    Using lemborexant with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

    Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

    Other drugs may affect lemborexant, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

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