Lenacapavir oral/injection

Generic name: Lenacapavir (oral/injection)
Brand names: Sunlenca
Drug class: Miscellaneous antivirals

Usage of Lenacapavir oral/injection

Lenacapavir is used in adults with other antiviral drugs to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Lenacapavir is not a cure for HIV or AIDS.

Lenacapavir is given after several other HIV medications did not work, have stopped working or could not be tolerated.

Lenacapavir may also be used for purposes not listed in this medication guide.

Lenacapavir oral/injection side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Lenacapavir can affect your immune system (even weeks or months after you've used lenacapavir). Tell your doctor if you have:

signs of a new infection--fever, night sweats, swollen glands, cold sores, cough, wheezing, diarrhea, weight loss;

trouble speaking or swallowing, problems with balance or eye movement, weakness or prickly feeling; or

swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence.

Common side effects of lenacapavir may include:

bruising, swelling, warmth, redness, oozing, or bleeding where an injection was given; or

nausea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Lenacapavir oral/injection

There may be other reasons you should not use lenacapavir in combination with certain medicines, such as efavirenz, Nevirapine, rifabutin, rifampin, rifapentine, Carbamazepine, oxcarbazepine, phenytoin, primidone, Dexamethasone, prednisone, St. John's wort, phenobarbital or other barbiturate medicine.

Tell your doctor if you have ever had:

an autoimmune disorder such as Graves' disease, polymyositis, or Guillain-Barré syndrome.

To prevent HIV in a newborn baby, use all medications to control your infection during pregnancy. Your name may be listed on an antiviral pregnancy registry.

It is not known if lenacapavir will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Women with HIV should not breastfeed. The virus can pass to your baby in your breast milk.

Relate drugs

How to use Lenacapavir oral/injection

Usual Adult Dose for HIV Infection:

Option 1:Initial dose:-Day 1: 927 mg suBCutaneously, 600 mg orally-Day 2: 600 mg orallyMaintenance dose:-Every 6 months (+/- 2 weeks): 927 mg subcutaneouslyOption 2:Initial dose:-Day 1: 600 mg orally-Day 2: 600 mg orally-Day 8: 300 mg orally-Day 15: 927 mg subcutaneouslyMaintenance dose:-Every 6 months (+/- 2 weeks): 927 mg subcutaneouslyUse: Treatment of human immunodeficiency virus type 1 (HIV-1) infection in heavily treatment-experienced adults having multidrug resistant HIV-1 infection unresponsive to current antiretroviral regimen due to resistance, intolerance, or safety considerations.

Warnings

Tell your doctor about all your other medicines. Some drugs should not be used with lenacapavir.

What other drugs will affect Lenacapavir oral/injection

Tell your doctor about all your current medicines. Many drugs can affect lenacapavir, especially:

phenobarbital or other barbiturate medicine;

St. John's wort;

an antibiotic--rifabutin, rifampin, rifapentine;

cancer medicine--apalutamide, Enzalutamide, mitotane;

HIV or AIDS medicine--efavirenz, nevirapine;

seizure medicine--carbamazepine, oxcarbazepine, phenytoin, primidone; or

steroid medicine--dexamethasone, prednisone.

This list is not complete and many other drugs may affect lenacapavir. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

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