Leqembi injection

Generic name: Lecanemab (injection)
Brand names: Leqembi
Drug class: Miscellaneous central nervous system agents

Usage of Leqembi injection

Lecanemab is used to treat adults with Alzheimer's disease.

Lecanemab may also be used for purposes not listed in this medication guide.

Leqembi injection side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your medical caregiver if you feel dizzy, nauseated, light-headed, itchy, sweaty, or have a headache, flu-like symptoms, fever, or vomiting; chest tightness, fast/slow heartbeats or pounding heartbeats, back pain, trouble breathing, or swelling in your face.

Common side effects of Leqembi may include:

ARIA with symptoms or with signs that appear on an MRI;

infusion-related reactions; or

headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Leqembi injection

Lecanemab can cause a condition called Amyloid Related Imaging Abnormalities or "ARIA" which is a temporary swelling or small spots of bleeding in the brain that usually clears up with time. Your doctor may perform an MRI of your brain before and during your treatment with lecanemab. Ask your doctor about your risk.

It is not known if lecanemab will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using this medicine.

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How to use Leqembi injection

Lecanemab is injected into a vein by a healthcare provider.

This medicine is injected slowly over 1 hour every 2 weeks.

You may be given other medications to help prevent serious side effects or allergic reaction.

Store this medicine in the refrigerator in the original container, do not freeze or shake.

Warnings

Lecanemab can cause temporary swelling or bleeding in the brain that usually clears up with time. This condition may cause no symptoms but can be serious. Call your doctor if you have headaches, dizziness, nausea, confusion, trouble with walking, seizures, or vision changes.

What other drugs will affect Leqembi injection

Tell your doctor about all your other medicines, especially medicines to treat or prevent blood clots, including aspirin.

Other drugs may affect lecanemab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Disclaimer

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