Lexapro

Generic name: Escitalopram
Drug class: Selective serotonin reuptake inhibitors

Usage of Lexapro

Lexapro (escitalopram) is an antidepressant from the group of drugs called selective serotonin reuptake inhibitors (SSRIs) and is used to treat certain types of depression and anxiety. It is not known how Lexapro works, but it is thought to block the reuptake of serotonin by nerves. This results in an increase in serotonin concentrations in the nerve synapse (the space between two nerves).

Lexapro side effects

Get emergency medical help if you have signs of an allergic reaction to Lexapro: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Lexapro may cause serious side effects. Call your doctor at once if you have:

  • blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
  • racing thoughts, unusual risk-taking behavior, feelings of extreme happiness or sadness;
  • pain or burning when you urinate;
  • (in a child taking Lexapro) slow growth or weight gain;
  • low levels of sodium in the body - headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady; or
  • severe nervous system reaction - very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.
  • Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

    Common side effects of Lexapro may include:

  • painful urination;
  • dizziness, drowsiness, tiredness, weakness;
  • feeling anxious or agitated;
  • increased muscle movements, feeling shaky;
  • sleep problems (insomnia);
  • sweating, dry mouth, increased thirst, loss of appetite;
  • nausea, constipation;
  • yawning;
  • nosebleed, heavy menstrual periods; or
  • decreased sex drive, impotence, or difficulty having an orgasm.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Lexapro

    You should not use Lexapro if you are allergic to escitalopram or citalopram (Celexa), or if:

  • you also take pimozide.
  • Do not use Lexapro within 14 days before or 14 days after you have used an MAO inhibitor. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

    Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. These medicines may interact with escitalopram and cause a serious condition called serotonin syndrome.

    To make sure Lexapro is safe for you, tell your doctor if you have ever had:

  • liver or kidney disease;
  • seizures;
  • low levels of sodium in your blood;
  • heart disease, high blood pressure;
  • a stroke;
  • bleeding problems;
  • sexual problems;
  • bipolar disorder (manic depression); or
  • drug addiction or suicidal thoughts.
  • Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

    Lexapro is not approved for use by anyone younger than 12 years old.

    Ask your doctor about taking this medicine if you are pregnant. Taking an SSRI antidepressant during late pregnancy may cause serious medical complications in the baby. However, you may have a relapse of depression if you stop taking your antidepressant. Tell your doctor right away if you become pregnant. Do not start or stop taking Lexapro without your doctor's advice.

    Pregnancy

    Ask your doctor about taking this medicine if you are pregnant. Taking an SSRI antidepressant during late pregnancy may cause serious medical complications in the baby. However, you may have a relapse of depression if you stop taking your antidepressant. Tell your doctor right away if you become pregnant. Do not start or stop taking Lexapro without your doctor's advice.

    If you are pregnant, your name may be listed on a pregnancy registry to track the effects of escitalopram on the baby.

    Breastfeeding

    If you are breastfeeding, tell your doctor if you notice drowsiness, agitation, feeding problems, or poor weight gain in the nursing baby.

    For more information on Lexapro use in pregnancy and breastfeeding click on the link below.

    Relate drugs

    How to use Lexapro

    Usual Adult Dose for Generalized Anxiety Disorder:

    Initial dose: 10 mg orally once a day; increase if necessary after at least 1 week of treatment to 20 mg once a day Maintenance dose: 10 to 20 mg orally once a day Maximum dose: 20 mg orally once a day Comment: Treatment should be periodically reassessed to determine the need for ongoing treatment; efficacy beyond 8 weeks has not been systematically studied. Use: Acute treatment of generalized anxiety disorder

    Usual Adult Dose for Depression:

    Initial dose: 10 mg orally once a day; increase if necessary after at least 1 week of treatment to 20 mg once a day Maintenance dose: 10 to 20 mg orally once a day Maximum dose: 20 mg orally once a day Comments: -Acute episodes may require several months or longer of sustained pharmacological therapy beyond response to the acute episode. -Patients should be periodically reassessed to determine the need for maintenance treatment. Use: Acute and maintenance treatment of major depressive disorder

    Usual Geriatric Dose for Depression:

    Recommended dose: 10 mg orally once a day Use: Acute and maintenance treatment of major depressive disorder

    Usual Pediatric Dose for Depression:

    12 years and older: -Initial dose: 10 mg orally once a day; increase if necessary after at least 3 weeks of treatment to 20 mg once a day -Maintenance dose: 10 to 20 mg orally once a day -Maximum dose: 20 mg orally once a day Comments: -Acute episodes may require several months or longer of sustained pharmacological therapy beyond response to the acute episode. -Patients should be periodically reassessed to determine the need for maintenance treatment. Use: Acute and maintenance treatment of major depressive disorder

    Warnings

    You should not use Lexapro if you also take pimozide or citalopram (Celexa).

    Do not use Lexapro within 14 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

    Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

    Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

    Do not give Lexapro to anyone under 12 years.

    Do not stop using Lexapro without first asking your doctor.

    What other drugs will affect Lexapro

    Using Lexapro with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

    Tell your doctor about all your current medicines, especially a blood thinner such as warfarin, Coumadin, or Jantoven.

    Many drugs may interact with escitalopram, and some drugs should not be used at the same time. Tell your doctor about all your current medicines and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

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    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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