Linagliptin

Generic name: Linagliptin
Brand names: Tradjenta
Dosage form: oral tablet (5 mg)
Drug class: Dipeptidyl peptidase 4 inhibitors

Usage of Linagliptin

Linagliptin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. linagliptin is not for treating type 1 diabetes.

Linagliptin may also be used for purposes not listed in this medication guide.

Linagliptin side effects

Get emergency medical help if you have signs of an allergic reaction (hives, rash, itching, peeling, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Stop taking linagliptin and call your doctor right away if you have symptoms of pancreatitis: severe pain in your upper stomach spreading to your back, with or without vomiting.

Linagliptin may cause serious side effects. Call your doctor at once if you have:

severe or ongoing pain in your joints;

a severe autoimmune reaction--itching, blisters, breakdown of the outer layer of skin; or

symptoms of heart failure--shortness of breath (even while lying down), swelling in your legs or feet, rapid weight gain.

Common side effects of linagliptin may include:

runny or stuffy nose, sore throat;

cough; or

diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Linagliptin

You should not use linagliptin if:

you have ever had a severe allergic reaction to linagliptin (breathing problems, swelling, severe skin rash); or

you have diabetic ketoacidosis (call your doctor for treatment).

Tell your doctor if you have ever had:

heart problems;

kidney disease;

pancreatitis;

high triglycerides (a type of fat in the blood);

gallstones; or

alcoholism.

Tell your doctor if you are pregnant or breastfeeding.

Follow your doctor's instructions about using this medicine if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.

This medicine is not approved for use by anyone younger than 18 years old.

Relate drugs

How to use Linagliptin

Usual Adult Dose for Diabetes Type 2:

Recommended dose: 5 mg orally once a dayComments: When used in combination with insulin or an insulin secretagogue, a lower dose of the insulin secretagogue or insulin may be necessary to reduce the risk of hypoglycemia.Use: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus

Warnings

linagliptin can cause severe, life-threatening pancreatitis (inflammation of your pancreas). Stop taking linagliptin and call your doctor at once if you have pain in your upper stomach that may spread to your back, with or without vomiting.

Also call your doctor if you have symptoms of heart failure, such as swelling, rapid weight gain, or shortness of breath (even while lying down).

What other drugs will affect Linagliptin

Other drugs may increase or decrease the effects of linagliptin on lowering your blood sugar. Tell your doctor about all your other medicines, especially:

rifampin (to treat tuberculosis); or

insulin or other oral diabetes medications.

This list is not complete. Other drugs may affect linagliptin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.